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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GATA2
Full Name:
Endothelial transcription factor GATA-2
Alias:
GATA binding protein 2; NFE1B
Type:
Transcription protein
Mass (Da):
50500
Number AA:
480
UniProt ID:
P23769
International Prot ID:
IPI00012900
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0006909
GO:0010552
GO:0050766
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
L
N
A
Q
H
P
D
S
H
H
P
G
L
A
H
Site 2
Y33
H
P
G
L
A
H
N
Y
M
E
P
A
Q
L
L
Site 3
Y59
L
D
S
Q
G
N
P
Y
Y
A
N
P
A
H
A
Site 4
Y60
D
S
Q
G
N
P
Y
Y
A
N
P
A
H
A
R
Site 5
S71
A
H
A
R
A
R
V
S
Y
S
P
A
H
A
R
Site 6
Y72
H
A
R
A
R
V
S
Y
S
P
A
H
A
R
L
Site 7
S73
A
R
A
R
V
S
Y
S
P
A
H
A
R
L
T
Site 8
T80
S
P
A
H
A
R
L
T
G
G
Q
M
C
R
P
Site 9
S92
C
R
P
H
L
L
H
S
P
G
L
P
W
L
D
Site 10
S106
D
G
G
K
A
A
L
S
A
A
A
A
H
H
H
Site 11
T117
A
H
H
H
N
P
W
T
V
S
P
F
S
K
T
Site 12
S119
H
H
N
P
W
T
V
S
P
F
S
K
T
P
L
Site 13
S122
P
W
T
V
S
P
F
S
K
T
P
L
H
P
S
Site 14
T124
T
V
S
P
F
S
K
T
P
L
H
P
S
A
A
Site 15
S129
S
K
T
P
L
H
P
S
A
A
G
G
P
G
G
Site 16
S139
G
G
P
G
G
P
L
S
V
Y
P
G
A
G
G
Site 17
Y141
P
G
G
P
L
S
V
Y
P
G
A
G
G
G
S
Site 18
S148
Y
P
G
A
G
G
G
S
G
G
G
S
G
S
S
Site 19
S152
G
G
G
S
G
G
G
S
G
S
S
V
A
S
L
Site 20
S154
G
S
G
G
G
S
G
S
S
V
A
S
L
T
P
Site 21
S155
S
G
G
G
S
G
S
S
V
A
S
L
T
P
T
Site 22
S158
G
S
G
S
S
V
A
S
L
T
P
T
A
A
H
Site 23
T160
G
S
S
V
A
S
L
T
P
T
A
A
H
S
G
Site 24
T162
S
V
A
S
L
T
P
T
A
A
H
S
G
S
H
Site 25
S168
P
T
A
A
H
S
G
S
H
L
F
G
F
P
P
Site 26
T176
H
L
F
G
F
P
P
T
P
P
K
E
V
S
P
Site 27
S182
P
T
P
P
K
E
V
S
P
D
P
S
T
T
G
Site 28
S186
K
E
V
S
P
D
P
S
T
T
G
A
A
S
P
Site 29
T187
E
V
S
P
D
P
S
T
T
G
A
A
S
P
A
Site 30
T188
V
S
P
D
P
S
T
T
G
A
A
S
P
A
S
Site 31
S192
P
S
T
T
G
A
A
S
P
A
S
S
S
A
G
Site 32
S195
T
G
A
A
S
P
A
S
S
S
A
G
G
S
A
Site 33
S196
G
A
A
S
P
A
S
S
S
A
G
G
S
A
A
Site 34
S197
A
A
S
P
A
S
S
S
A
G
G
S
A
A
R
Site 35
S201
A
S
S
S
A
G
G
S
A
A
R
G
E
D
K
Site 36
Y213
E
D
K
D
G
V
K
Y
Q
V
S
L
T
E
S
Site 37
S216
D
G
V
K
Y
Q
V
S
L
T
E
S
M
K
M
Site 38
T218
V
K
Y
Q
V
S
L
T
E
S
M
K
M
E
S
Site 39
S220
Y
Q
V
S
L
T
E
S
M
K
M
E
S
G
S
Site 40
S225
T
E
S
M
K
M
E
S
G
S
P
L
R
P
G
Site 41
S227
S
M
K
M
E
S
G
S
P
L
R
P
G
L
A
Site 42
T235
P
L
R
P
G
L
A
T
M
G
T
Q
P
A
T
Site 43
T238
P
G
L
A
T
M
G
T
Q
P
A
T
H
H
P
Site 44
T242
T
M
G
T
Q
P
A
T
H
H
P
I
P
T
Y
Site 45
Y249
T
H
H
P
I
P
T
Y
P
S
Y
V
P
A
A
Site 46
S251
H
P
I
P
T
Y
P
S
Y
V
P
A
A
A
H
Site 47
Y252
P
I
P
T
Y
P
S
Y
V
P
A
A
A
H
D
Site 48
Y260
V
P
A
A
A
H
D
Y
S
S
G
L
F
H
P
Site 49
S261
P
A
A
A
H
D
Y
S
S
G
L
F
H
P
G
Site 50
S262
A
A
A
H
D
Y
S
S
G
L
F
H
P
G
G
Site 51
S276
G
F
L
G
G
P
A
S
S
F
T
P
K
Q
R
Site 52
S277
F
L
G
G
P
A
S
S
F
T
P
K
Q
R
S
Site 53
T279
G
G
P
A
S
S
F
T
P
K
Q
R
S
K
A
Site 54
S284
S
F
T
P
K
Q
R
S
K
A
R
S
C
S
E
Site 55
S288
K
Q
R
S
K
A
R
S
C
S
E
G
R
E
C
Site 56
S290
R
S
K
A
R
S
C
S
E
G
R
E
C
V
N
Site 57
T303
V
N
C
G
A
T
A
T
P
L
W
R
R
D
G
Site 58
T311
P
L
W
R
R
D
G
T
G
H
Y
L
C
N
A
Site 59
Y314
R
R
D
G
T
G
H
Y
L
C
N
A
C
G
L
Site 60
Y322
L
C
N
A
C
G
L
Y
H
K
M
N
G
Q
N
Site 61
S340
I
K
P
K
R
R
L
S
A
A
R
R
A
G
T
Site 62
T347
S
A
A
R
R
A
G
T
C
C
A
N
C
Q
T
Site 63
Y376
V
C
N
A
C
G
L
Y
Y
K
L
H
N
V
N
Site 64
T387
H
N
V
N
R
P
L
T
M
K
K
E
G
I
Q
Site 65
T395
M
K
K
E
G
I
Q
T
R
N
R
K
M
S
N
Site 66
S401
Q
T
R
N
R
K
M
S
N
K
S
K
K
S
K
Site 67
S407
M
S
N
K
S
K
K
S
K
K
G
A
E
C
F
Site 68
S425
S
K
C
M
Q
E
K
S
S
P
F
S
A
A
A
Site 69
S426
K
C
M
Q
E
K
S
S
P
F
S
A
A
A
L
Site 70
S429
Q
E
K
S
S
P
F
S
A
A
A
L
A
G
H
Site 71
S449
H
L
P
P
F
S
H
S
G
H
I
L
P
T
P
Site 72
T455
H
S
G
H
I
L
P
T
P
T
P
I
H
P
S
Site 73
T457
G
H
I
L
P
T
P
T
P
I
H
P
S
S
S
Site 74
S462
T
P
T
P
I
H
P
S
S
S
L
S
F
G
H
Site 75
S463
P
T
P
I
H
P
S
S
S
L
S
F
G
H
P
Site 76
S464
T
P
I
H
P
S
S
S
L
S
F
G
H
P
H
Site 77
S466
I
H
P
S
S
S
L
S
F
G
H
P
H
P
S
Site 78
S473
S
F
G
H
P
H
P
S
S
M
V
T
A
M
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation