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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB25
Full Name:
Zinc finger and BTB domain-containing protein 25
Alias:
Zinc finger protein 46;Zinc finger protein KUP
Type:
Mass (Da):
48990
Number AA:
435
UniProt ID:
P24278
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y81
S
Y
L
L
H
I
M
Y
T
G
K
G
P
K
Q
Site 2
S93
P
K
Q
I
V
D
H
S
R
L
E
E
G
I
R
Site 3
T112
D
Y
L
S
H
I
A
T
E
M
N
Q
V
F
S
Site 4
S119
T
E
M
N
Q
V
F
S
P
E
T
V
Q
S
S
Site 5
T122
N
Q
V
F
S
P
E
T
V
Q
S
S
N
L
Y
Site 6
S125
F
S
P
E
T
V
Q
S
S
N
L
Y
G
I
Q
Site 7
Y129
T
V
Q
S
S
N
L
Y
G
I
Q
I
S
T
T
Site 8
T139
Q
I
S
T
T
Q
K
T
V
V
K
Q
G
L
E
Site 9
S153
E
V
K
E
A
P
S
S
N
S
G
N
R
A
A
Site 10
S171
D
H
P
Q
L
Q
L
S
L
A
I
G
L
D
D
Site 11
T180
A
I
G
L
D
D
G
T
A
D
Q
Q
R
A
C
Site 12
T190
Q
Q
R
A
C
P
A
T
Q
A
L
E
E
H
Q
Site 13
S202
E
H
Q
K
P
P
V
S
I
K
Q
E
R
C
D
Site 14
S212
Q
E
R
C
D
P
E
S
V
I
S
Q
S
H
P
Site 15
S215
C
D
P
E
S
V
I
S
Q
S
H
P
S
P
S
Site 16
S217
P
E
S
V
I
S
Q
S
H
P
S
P
S
S
E
Site 17
S220
V
I
S
Q
S
H
P
S
P
S
S
E
V
T
G
Site 18
S222
S
Q
S
H
P
S
P
S
S
E
V
T
G
P
T
Site 19
S223
Q
S
H
P
S
P
S
S
E
V
T
G
P
T
F
Site 20
T226
P
S
P
S
S
E
V
T
G
P
T
F
T
E
N
Site 21
T229
S
S
E
V
T
G
P
T
F
T
E
N
S
V
K
Site 22
S249
Y
C
G
E
R
F
D
S
R
S
N
L
R
Q
H
Site 23
S251
G
E
R
F
D
S
R
S
N
L
R
Q
H
L
H
Site 24
T259
N
L
R
Q
H
L
H
T
H
V
S
G
S
L
P
Site 25
S262
Q
H
L
H
T
H
V
S
G
S
L
P
F
G
V
Site 26
S276
V
P
A
S
I
L
E
S
N
D
L
G
E
V
H
Site 27
S298
A
L
E
C
R
R
L
S
S
F
I
V
K
E
N
Site 28
S299
L
E
C
R
R
L
S
S
F
I
V
K
E
N
E
Site 29
T312
N
E
Q
Q
P
D
H
T
N
R
G
T
T
E
P
Site 30
T316
P
D
H
T
N
R
G
T
T
E
P
L
Q
I
S
Site 31
T317
D
H
T
N
R
G
T
T
E
P
L
Q
I
S
Q
Site 32
S323
T
T
E
P
L
Q
I
S
Q
V
S
L
I
S
K
Site 33
S326
P
L
Q
I
S
Q
V
S
L
I
S
K
D
T
E
Site 34
T332
V
S
L
I
S
K
D
T
E
P
V
E
L
N
C
Site 35
S342
V
E
L
N
C
N
F
S
F
S
R
K
R
K
M
Site 36
S362
G
H
K
F
P
R
K
S
Q
L
L
E
H
M
Y
Site 37
Y369
S
Q
L
L
E
H
M
Y
T
H
K
G
K
S
Y
Site 38
T370
Q
L
L
E
H
M
Y
T
H
K
G
K
S
Y
R
Site 39
Y378
H
K
G
K
S
Y
R
Y
N
R
C
Q
R
F
G
Site 40
Y395
L
A
Q
R
F
Q
P
Y
C
D
S
W
S
D
V
Site 41
S398
R
F
Q
P
Y
C
D
S
W
S
D
V
S
L
K
Site 42
S400
Q
P
Y
C
D
S
W
S
D
V
S
L
K
S
S
Site 43
S403
C
D
S
W
S
D
V
S
L
K
S
S
R
L
S
Site 44
S406
W
S
D
V
S
L
K
S
S
R
L
S
Q
E
H
Site 45
S407
S
D
V
S
L
K
S
S
R
L
S
Q
E
H
L
Site 46
S410
S
L
K
S
S
R
L
S
Q
E
H
L
D
L
P
Site 47
T425
C
A
L
E
S
E
L
T
Q
E
N
V
D
T
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation