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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP3A7
Full Name:
Cytochrome P450 3A7
Alias:
CYPIIIA7;Cytochrome P450-HFLA
Type:
Mass (Da):
57526
Number AA:
503
UniProt ID:
P24462
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
P
F
L
G
N
A
L
S
F
R
K
G
Y
W
T
Site 2
Y57
A
L
S
F
R
K
G
Y
W
T
F
D
M
E
C
Site 3
Y68
D
M
E
C
Y
K
K
Y
R
K
V
W
G
I
Y
Site 4
Y75
Y
R
K
V
W
G
I
Y
D
C
Q
Q
P
M
L
Site 5
T92
T
D
P
D
M
I
K
T
V
L
V
K
E
C
Y
Site 6
Y99
T
V
L
V
K
E
C
Y
S
V
F
T
N
R
R
Site 7
T103
K
E
C
Y
S
V
F
T
N
R
R
P
F
G
P
Site 8
S119
G
F
M
K
N
A
I
S
I
A
E
D
E
E
W
Site 9
S131
E
E
W
K
R
I
R
S
L
L
S
P
T
F
T
Site 10
S134
K
R
I
R
S
L
L
S
P
T
F
T
S
G
K
Site 11
T136
I
R
S
L
L
S
P
T
F
T
S
G
K
L
K
Site 12
T138
S
L
L
S
P
T
F
T
S
G
K
L
K
E
M
Site 13
T166
N
L
R
R
E
A
E
T
G
K
P
V
T
L
K
Site 14
S192
T
S
T
S
F
G
V
S
I
D
S
L
N
N
P
Site 15
S195
S
F
G
V
S
I
D
S
L
N
N
P
Q
D
P
Site 16
T250
R
K
V
I
S
F
L
T
K
S
V
K
Q
I
K
Site 17
S278
F
L
Q
L
M
I
D
S
Q
N
S
K
D
S
E
Site 18
S284
D
S
Q
N
S
K
D
S
E
T
H
K
A
L
S
Site 19
S291
S
E
T
H
K
A
L
S
D
L
E
L
M
A
Q
Site 20
T337
K
V
Q
K
E
I
D
T
V
L
P
N
K
A
P
Site 21
T346
L
P
N
K
A
P
P
T
Y
D
T
V
L
Q
L
Site 22
Y347
P
N
K
A
P
P
T
Y
D
T
V
L
Q
L
E
Site 23
T349
K
A
P
P
T
Y
D
T
V
L
Q
L
E
Y
L
Site 24
Y407
V
L
H
H
D
P
K
Y
W
R
E
P
E
K
F
Site 25
S420
K
F
L
P
E
R
F
S
K
K
N
K
D
N
I
Site 26
Y430
N
K
D
N
I
D
P
Y
I
Y
T
P
F
G
S
Site 27
Y432
D
N
I
D
P
Y
I
Y
T
P
F
G
S
G
P
Site 28
T433
N
I
D
P
Y
I
Y
T
P
F
G
S
G
P
R
Site 29
S464
V
R
V
L
Q
N
F
S
F
K
P
C
K
E
T
Site 30
T471
S
F
K
P
C
K
E
T
Q
I
P
L
K
L
R
Site 31
T485
R
F
G
G
L
L
L
T
E
K
P
I
V
L
K
Site 32
T499
K
A
E
S
R
D
E
T
V
S
G
A
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation