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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBXAS1
Full Name:
Thromboxane-A synthase
Alias:
Cytochrome P450 5A1
Type:
Mass (Da):
60518
Number AA:
533
UniProt ID:
P24557
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T33
A
L
L
K
W
Y
S
T
S
A
F
S
R
L
E
Site 2
S50
G
L
R
H
P
K
P
S
P
F
I
G
N
L
T
Site 3
T57
S
P
F
I
G
N
L
T
F
F
R
Q
G
F
W
Site 4
S66
F
R
Q
G
F
W
E
S
Q
M
E
L
R
K
L
Site 5
Y74
Q
M
E
L
R
K
L
Y
G
P
L
C
G
Y
Y
Site 6
S91
R
R
M
F
I
V
I
S
E
P
D
M
I
K
Q
Site 7
S113
N
F
T
N
R
M
A
S
G
L
E
F
K
S
V
Site 8
S123
E
F
K
S
V
A
D
S
V
L
F
L
R
D
K
Site 9
S141
E
V
R
G
A
L
M
S
A
F
S
P
E
K
L
Site 10
S144
G
A
L
M
S
A
F
S
P
E
K
L
N
E
M
Site 11
Y169
L
L
A
H
L
K
R
Y
A
E
S
G
D
A
F
Site 12
Y185
I
Q
R
C
Y
C
N
Y
T
T
D
V
V
A
S
Site 13
S288
M
V
L
D
A
R
H
S
A
S
P
M
G
V
Q
Site 14
S290
L
D
A
R
H
S
A
S
P
M
G
V
Q
D
F
Site 15
S306
I
V
R
D
V
F
S
S
T
G
C
K
P
N
P
Site 16
S314
T
G
C
K
P
N
P
S
R
Q
H
Q
P
S
P
Site 17
S320
P
S
R
Q
H
Q
P
S
P
M
A
R
P
L
T
Site 18
T327
S
P
M
A
R
P
L
T
V
D
E
I
V
G
Q
Site 19
S385
H
M
A
P
E
F
C
S
L
E
E
G
L
P
Y
Site 20
T411
Y
P
P
A
F
R
F
T
R
E
A
A
Q
D
C
Site 21
S447
H
D
P
E
H
W
P
S
P
E
T
F
N
P
E
Site 22
T450
E
H
W
P
S
P
E
T
F
N
P
E
R
F
T
Site 23
T457
T
F
N
P
E
R
F
T
A
E
A
R
Q
Q
H
Site 24
T468
R
Q
Q
H
R
P
F
T
Y
L
P
F
G
A
G
Site 25
Y469
Q
Q
H
R
P
F
T
Y
L
P
F
G
A
G
P
Site 26
T508
R
F
Q
A
C
P
E
T
Q
V
P
L
Q
L
E
Site 27
S516
Q
V
P
L
Q
L
E
S
K
S
A
L
G
P
K
Site 28
S518
P
L
Q
L
E
S
K
S
A
L
G
P
K
N
G
Site 29
Y527
L
G
P
K
N
G
V
Y
I
K
I
V
S
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation