PhosphoNET

           
Protein Info 
   
Short Name:  IGFBP6
Full Name:  Insulin-like growth factor-binding protein 6
Alias: 
Type: 
Mass (Da):  25322
Number AA:  240
UniProt ID:  P24592
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S52VEEEDGGSPAEGCAE
Site 2Y74EGQECGVYTPNCAPG
Site 3T75GQECGVYTPNCAPGL
Site 4S144QQRNPGTSTTPSQPN
Site 5T145QRNPGTSTTPSQPNS
Site 6T146RNPGTSTTPSQPNSA
Site 7S148PGTSTTPSQPNSAGV
Site 8S152TTPSQPNSAGVQDTE
Site 9S169PCRRHLDSVLQQLQT
Site 10T176SVLQQLQTEVYRGAQ
Site 11Y186YRGAQTLYVPNCDHR
Site 12Y196NCDHRGFYRKRQCRS
Site 13S204RKRQCRSSQGQRRGP
Site 14S221CVDRMGKSLPGSPDG
Site 15S225MGKSLPGSPDGNGSS
Site 16S231GSPDGNGSSSCPTGS
Site 17S232SPDGNGSSSCPTGSS
Site 18S233PDGNGSSSCPTGSSG
Site 19T236NGSSSCPTGSSG___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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