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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TACR1
Full Name:
Substance-P receptor
Alias:
NK-1 receptor;Tachykinin receptor 1
Type:
Mass (Da):
46251
Number AA:
407
UniProt ID:
P25103
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
D
N
V
L
P
V
D
S
D
L
S
P
N
I
S
Site 2
S12
L
P
V
D
S
D
L
S
P
N
I
S
T
N
T
Site 3
S16
S
D
L
S
P
N
I
S
T
N
T
S
E
P
N
Site 4
S20
P
N
I
S
T
N
T
S
E
P
N
Q
F
V
Q
Site 5
T65
L
A
H
K
R
M
R
T
V
T
N
Y
F
L
V
Site 6
T67
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
Site 7
S143
H
P
L
Q
P
R
L
S
A
T
A
T
K
V
V
Site 8
S169
A
F
P
Q
G
Y
Y
S
T
T
E
T
M
P
S
Site 9
T173
G
Y
Y
S
T
T
E
T
M
P
S
R
V
V
C
Site 10
Y192
P
E
H
P
N
K
I
Y
E
K
V
Y
H
I
C
Site 11
S233
S
E
I
P
G
D
S
S
D
R
Y
H
E
Q
V
Site 12
Y236
P
G
D
S
S
D
R
Y
H
E
Q
V
S
A
K
Site 13
S241
D
R
Y
H
E
Q
V
S
A
K
R
K
V
V
K
Site 14
Y278
P
Y
I
N
P
D
L
Y
L
K
K
F
I
Q
Q
Site 15
Y331
P
F
I
S
A
G
D
Y
E
G
L
E
M
K
S
Site 16
S338
Y
E
G
L
E
M
K
S
T
R
Y
L
Q
T
Q
Site 17
T339
E
G
L
E
M
K
S
T
R
Y
L
Q
T
Q
G
Site 18
Y341
L
E
M
K
S
T
R
Y
L
Q
T
Q
G
S
V
Site 19
T344
K
S
T
R
Y
L
Q
T
Q
G
S
V
Y
K
V
Site 20
S347
R
Y
L
Q
T
Q
G
S
V
Y
K
V
S
R
L
Site 21
S359
S
R
L
E
T
T
I
S
T
V
V
G
A
H
E
Site 22
T360
R
L
E
T
T
I
S
T
V
V
G
A
H
E
E
Site 23
T376
P
E
D
G
P
K
A
T
P
S
S
L
D
L
T
Site 24
S378
D
G
P
K
A
T
P
S
S
L
D
L
T
S
N
Site 25
S379
G
P
K
A
T
P
S
S
L
D
L
T
S
N
C
Site 26
T383
T
P
S
S
L
D
L
T
S
N
C
S
S
R
S
Site 27
S384
P
S
S
L
D
L
T
S
N
C
S
S
R
S
D
Site 28
S387
L
D
L
T
S
N
C
S
S
R
S
D
S
K
T
Site 29
S388
D
L
T
S
N
C
S
S
R
S
D
S
K
T
M
Site 30
S390
T
S
N
C
S
S
R
S
D
S
K
T
M
T
E
Site 31
S392
N
C
S
S
R
S
D
S
K
T
M
T
E
S
F
Site 32
T394
S
S
R
S
D
S
K
T
M
T
E
S
F
S
F
Site 33
T396
R
S
D
S
K
T
M
T
E
S
F
S
F
S
S
Site 34
S398
D
S
K
T
M
T
E
S
F
S
F
S
S
N
V
Site 35
S400
K
T
M
T
E
S
F
S
F
S
S
N
V
L
S
Site 36
S402
M
T
E
S
F
S
F
S
S
N
V
L
S
_
_
Site 37
S403
T
E
S
F
S
F
S
S
N
V
L
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation