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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MPST
Full Name:
3-mercaptopyruvate sulfurtransferase
Alias:
3-mercaptopyruvate sulfurtransferase variant; Liver rhodanese; Mercaptopyruvate sulfurtransferase; MST; THTM; TST2
Type:
Transferase; Amino Acid Metabolism - cysteine and methionine; EC 2.8.1.2
Mass (Da):
33178
Number AA:
297
UniProt ID:
P25325
International Prot ID:
IPI00165360
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0016784
GO:0004792
PhosphoSite+
KinaseNET
Biological Process:
GO:0009440
GO:0009636
GO:0008272
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
P
Q
L
C
R
A
L
Site 2
S35
P
L
Q
L
L
D
A
S
W
Y
L
P
K
L
G
Site 3
Y37
Q
L
L
D
A
S
W
Y
L
P
K
L
G
R
D
Site 4
S70
D
Q
C
S
D
R
T
S
P
Y
D
H
M
L
P
Site 5
Y72
C
S
D
R
T
S
P
Y
D
H
M
L
P
G
A
Site 6
Y85
G
A
E
H
F
A
E
Y
A
G
R
L
G
V
G
Site 7
Y108
D
A
S
D
Q
G
L
Y
S
A
P
R
V
W
W
Site 8
S143
L
R
Q
N
L
P
L
S
S
G
K
S
Q
P
A
Site 9
S144
R
Q
N
L
P
L
S
S
G
K
S
Q
P
A
P
Site 10
S147
L
P
L
S
S
G
K
S
Q
P
A
P
A
E
F
Site 11
T165
L
D
P
A
F
I
K
T
Y
E
D
I
K
E
N
Site 12
Y166
D
P
A
F
I
K
T
Y
E
D
I
K
E
N
L
Site 13
S175
D
I
K
E
N
L
E
S
R
R
F
Q
V
V
D
Site 14
T186
Q
V
V
D
S
R
A
T
G
R
F
R
G
T
E
Site 15
T192
A
T
G
R
F
R
G
T
E
P
E
P
R
D
G
Site 16
T208
E
P
G
H
I
P
G
T
V
N
I
P
F
T
D
Site 17
T214
G
T
V
N
I
P
F
T
D
F
L
S
Q
E
G
Site 18
S218
I
P
F
T
D
F
L
S
Q
E
G
L
E
K
S
Site 19
S225
S
Q
E
G
L
E
K
S
P
E
E
I
R
H
L
Site 20
S250
P
L
V
A
T
C
G
S
G
V
T
A
C
H
V
Site 21
Y272
G
K
P
D
V
P
I
Y
D
G
S
W
V
E
W
Site 22
Y280
D
G
S
W
V
E
W
Y
M
R
A
R
P
E
D
Site 23
S290
A
R
P
E
D
V
I
S
E
G
R
G
K
T
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation