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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP5A1
Full Name:
ATP synthase subunit alpha, mitochondrial
Alias:
ATP synthase alpha chain, mitochondrial precursor; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; ATP5A; ATP5AL2; ATPA; ATPM; OMR; ORM
Type:
Energy Metabolism - oxidative phosphorylation; Transporter; Membrane protein, integral; Mitochondrial; Hydrolase; EC 3.6.3.14
Mass (Da):
59751
Number AA:
553
UniProt ID:
P25705
International Prot ID:
IPI00440493
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042288
GO:0043499
PhosphoSite+
KinaseNET
Biological Process:
GO:0009790
GO:0006629
GO:0042776
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
P
R
R
A
G
L
V
S
R
N
A
L
G
S
S
Site 2
S28
V
S
R
N
A
L
G
S
S
F
I
A
A
R
N
Site 3
S29
S
R
N
A
L
G
S
S
F
I
A
A
R
N
F
Site 4
S39
A
A
R
N
F
H
A
S
N
T
H
L
Q
K
T
Site 5
T46
S
N
T
H
L
Q
K
T
G
T
A
E
M
S
S
Site 6
T48
T
H
L
Q
K
T
G
T
A
E
M
S
S
I
L
Site 7
S52
K
T
G
T
A
E
M
S
S
I
L
E
E
R
I
Site 8
S53
T
G
T
A
E
M
S
S
I
L
E
E
R
I
L
Site 9
S65
R
I
L
G
A
D
T
S
V
D
L
E
E
T
G
Site 10
T71
T
S
V
D
L
E
E
T
G
R
V
L
S
I
G
Site 11
S76
E
E
T
G
R
V
L
S
I
G
D
G
I
A
R
Site 12
S99
A
E
E
M
V
E
F
S
S
G
L
K
G
M
S
Site 13
S100
E
E
M
V
E
F
S
S
G
L
K
G
M
S
L
Site 14
S106
S
S
G
L
K
G
M
S
L
N
L
E
P
D
N
Site 15
S166
D
G
K
G
P
I
G
S
K
T
R
R
R
V
G
Site 16
T168
K
G
P
I
G
S
K
T
R
R
R
V
G
L
K
Site 17
S184
P
G
I
I
P
R
I
S
V
R
E
P
M
Q
T
Site 18
T191
S
V
R
E
P
M
Q
T
G
I
K
A
V
D
S
Site 19
T219
G
D
R
Q
T
G
K
T
S
I
A
I
D
T
I
Site 20
T225
K
T
S
I
A
I
D
T
I
I
N
Q
K
R
F
Site 21
S236
Q
K
R
F
N
D
G
S
D
E
K
K
K
L
Y
Site 22
Y243
S
D
E
K
K
K
L
Y
C
I
Y
V
A
I
G
Site 23
Y246
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Site 24
S254
V
A
I
G
Q
K
R
S
T
V
A
Q
L
V
K
Site 25
T255
A
I
G
Q
K
R
S
T
V
A
Q
L
V
K
R
Site 26
T264
A
Q
L
V
K
R
L
T
D
A
D
A
M
K
Y
Site 27
Y287
S
D
A
A
P
L
Q
Y
L
A
P
Y
S
G
C
Site 28
Y291
P
L
Q
Y
L
A
P
Y
S
G
C
S
M
G
E
Site 29
S292
L
Q
Y
L
A
P
Y
S
G
C
S
M
G
E
Y
Site 30
Y299
S
G
C
S
M
G
E
Y
F
R
D
N
G
K
H
Site 31
Y311
G
K
H
A
L
I
I
Y
D
D
L
S
K
Q
A
Site 32
S315
L
I
I
Y
D
D
L
S
K
Q
A
V
A
Y
R
Site 33
S325
A
V
A
Y
R
Q
M
S
L
L
L
R
R
P
P
Site 34
Y337
R
P
P
G
R
E
A
Y
P
G
D
V
F
Y
L
Site 35
Y343
A
Y
P
G
D
V
F
Y
L
H
S
R
L
L
E
Site 36
S378
E
T
Q
A
G
D
V
S
A
Y
I
P
T
N
V
Site 37
S413
P
A
I
N
V
G
L
S
V
S
R
V
G
S
A
Site 38
S419
L
S
V
S
R
V
G
S
A
A
Q
T
R
A
M
Site 39
T423
R
V
G
S
A
A
Q
T
R
A
M
K
Q
V
A
Site 40
T432
A
M
K
Q
V
A
G
T
M
K
L
E
L
A
Q
Site 41
Y440
M
K
L
E
L
A
Q
Y
R
E
V
A
A
F
A
Site 42
S451
A
A
F
A
Q
F
G
S
D
L
D
A
A
T
Q
Site 43
T457
G
S
D
L
D
A
A
T
Q
Q
L
L
S
R
G
Site 44
T468
L
S
R
G
V
R
L
T
E
L
L
K
Q
G
Q
Site 45
S477
L
L
K
Q
G
Q
Y
S
P
M
A
I
E
E
Q
Site 46
Y495
I
Y
A
G
V
R
G
Y
L
D
K
L
E
P
S
Site 47
S513
K
F
E
N
A
F
L
S
H
V
V
S
Q
H
Q
Site 48
S517
A
F
L
S
H
V
V
S
Q
H
Q
A
L
L
G
Site 49
S536
D
G
K
I
S
E
Q
S
D
A
K
L
K
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation