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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMA2
Full Name:
Proteasome subunit alpha type-2
Alias:
C3; EC 3.4.25.1; HC3; Macropain subunit C3; MU; Multicatalytic endopeptidase complex subunit C3; PMSA2; Proteasome (prosome, macropain) subunit, alpha type, 2; PSA2; PSC3
Type:
EC 3.4.25.1; Protease; Proteasome complex
Mass (Da):
25899
Number AA:
234
UniProt ID:
P25787
International Prot ID:
IPI00219622
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005839
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004298
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
A
E
R
G
Y
S
F
S
L
T
T
F
Site 2
S7
_
M
A
E
R
G
Y
S
F
S
L
T
T
F
S
Site 3
S9
A
E
R
G
Y
S
F
S
L
T
T
F
S
P
S
Site 4
T11
R
G
Y
S
F
S
L
T
T
F
S
P
S
G
K
Site 5
T12
G
Y
S
F
S
L
T
T
F
S
P
S
G
K
L
Site 6
S14
S
F
S
L
T
T
F
S
P
S
G
K
L
V
Q
Site 7
Y24
G
K
L
V
Q
I
E
Y
A
L
A
A
V
A
G
Site 8
S54
A
T
E
K
K
Q
K
S
I
L
Y
D
E
R
S
Site 9
Y57
K
K
Q
K
S
I
L
Y
D
E
R
S
V
H
K
Site 10
S61
S
I
L
Y
D
E
R
S
V
H
K
V
E
P
I
Site 11
Y76
T
K
H
I
G
L
V
Y
S
G
M
G
P
D
Y
Site 12
S77
K
H
I
G
L
V
Y
S
G
M
G
P
D
Y
R
Site 13
Y83
Y
S
G
M
G
P
D
Y
R
V
L
V
H
R
A
Site 14
Y97
A
R
K
L
A
Q
Q
Y
Y
L
V
Y
Q
E
P
Site 15
Y98
R
K
L
A
Q
Q
Y
Y
L
V
Y
Q
E
P
I
Site 16
Y101
A
Q
Q
Y
Y
L
V
Y
Q
E
P
I
P
T
A
Site 17
S116
Q
L
V
Q
R
V
A
S
V
M
Q
E
Y
T
Q
Site 18
Y121
V
A
S
V
M
Q
E
Y
T
Q
S
G
G
V
R
Site 19
S124
V
M
Q
E
Y
T
Q
S
G
G
V
R
P
F
G
Site 20
Y145
G
W
N
E
G
R
P
Y
L
F
Q
S
D
P
S
Site 21
S149
G
R
P
Y
L
F
Q
S
D
P
S
G
A
Y
F
Site 22
Y155
Q
S
D
P
S
G
A
Y
F
A
W
K
A
T
A
Site 23
Y167
A
T
A
M
G
K
N
Y
V
N
G
K
T
F
L
Site 24
T172
K
N
Y
V
N
G
K
T
F
L
E
K
R
Y
N
Site 25
S198
A
I
L
T
L
K
E
S
F
E
G
Q
M
T
E
Site 26
T204
E
S
F
E
G
Q
M
T
E
D
N
I
E
V
G
Site 27
T222
E
A
G
F
R
R
L
T
P
T
E
V
K
D
Y
Site 28
T224
G
F
R
R
L
T
P
T
E
V
K
D
Y
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation