KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PSMA4
Full Name:
Proteasome subunit alpha type-4
Alias:
EC 3.4.25.1; Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit HC9; Proteasome subunit L; PSA4; PSC9
Type:
Proteasome core complex, Cytoplasm, Cytosol, Nucleus protein
Mass (Da):
29484
Number AA:
261
UniProt ID:
P25789
International Prot ID:
IPI00299155
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005839
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0004298
GO:0004298
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
R
R
Y
D
S
R
T
T
I
F
S
P
Site 2
T9
S
R
R
Y
D
S
R
T
T
I
F
S
P
E
G
Site 3
T10
R
R
Y
D
S
R
T
T
I
F
S
P
E
G
R
Site 4
S13
D
S
R
T
T
I
F
S
P
E
G
R
L
Y
Q
Site 5
Y19
F
S
P
E
G
R
L
Y
Q
V
E
Y
A
M
E
Site 6
Y23
G
R
L
Y
Q
V
E
Y
A
M
E
A
I
G
H
Site 7
Y66
V
F
F
S
E
K
I
Y
K
L
N
E
D
M
A
Site 8
S75
L
N
E
D
M
A
C
S
V
A
G
I
T
S
D
Site 9
T80
A
C
S
V
A
G
I
T
S
D
A
N
V
L
T
Site 10
S81
C
S
V
A
G
I
T
S
D
A
N
V
L
T
N
Site 11
Y97
L
R
L
I
A
Q
R
Y
L
L
Q
Y
Q
E
P
Site 12
Y101
A
Q
R
Y
L
L
Q
Y
Q
E
P
I
P
C
E
Site 13
Y121
L
C
D
I
K
Q
A
Y
T
Q
F
G
G
K
R
Site 14
Y143
Y
I
G
W
D
K
H
Y
G
F
Q
L
Y
Q
S
Site 15
Y148
K
H
Y
G
F
Q
L
Y
Q
S
D
P
S
G
N
Site 16
S150
Y
G
F
Q
L
Y
Q
S
D
P
S
G
N
Y
G
Site 17
S153
Q
L
Y
Q
S
D
P
S
G
N
Y
G
G
W
K
Site 18
Y156
Q
S
D
P
S
G
N
Y
G
G
W
K
A
T
C
Site 19
Y179
V
S
M
L
K
Q
D
Y
K
E
G
E
M
T
L
Site 20
T185
D
Y
K
E
G
E
M
T
L
K
S
A
L
A
L
Site 21
S204
L
N
K
T
M
D
V
S
K
L
S
A
E
K
V
Site 22
T223
L
T
R
E
N
G
K
T
V
I
R
V
L
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation