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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HMGB2
Full Name:
High mobility group protein B2
Alias:
High mobility group protein 2; High-mobility group box 2; HMG2
Type:
Nuclear receptor co-regulator; DNA binding protein
Mass (Da):
24034
Number AA:
209
UniProt ID:
P26583
International Prot ID:
IPI00219097
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000793
GO:0000228
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0008301
GO:0003690
GO:0016565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006268
GO:0006288
GO:0016481
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
P
R
G
K
M
S
S
Y
A
F
F
V
Q
T
Site 2
Y16
P
R
G
K
M
S
S
Y
A
F
F
V
Q
T
C
Site 3
T22
S
Y
A
F
F
V
Q
T
C
R
E
E
H
K
K
Site 4
S34
H
K
K
K
H
P
D
S
S
V
N
F
A
E
F
Site 5
S35
K
K
K
H
P
D
S
S
V
N
F
A
E
F
S
Site 6
S42
S
V
N
F
A
E
F
S
K
K
C
S
E
R
W
Site 7
S46
A
E
F
S
K
K
C
S
E
R
W
K
T
M
S
Site 8
T51
K
C
S
E
R
W
K
T
M
S
A
K
E
K
S
Site 9
S53
S
E
R
W
K
T
M
S
A
K
E
K
S
K
F
Site 10
S58
T
M
S
A
K
E
K
S
K
F
E
D
M
A
K
Site 11
S66
K
F
E
D
M
A
K
S
D
K
A
R
Y
D
R
Site 12
Y71
A
K
S
D
K
A
R
Y
D
R
E
M
K
N
Y
Site 13
Y78
Y
D
R
E
M
K
N
Y
V
P
P
K
G
D
K
Site 14
S100
N
A
P
K
R
P
P
S
A
F
F
L
F
C
S
Site 15
S107
S
A
F
F
L
F
C
S
E
H
R
P
K
I
K
Site 16
S115
E
H
R
P
K
I
K
S
E
H
P
G
L
S
I
Site 17
S121
K
S
E
H
P
G
L
S
I
G
D
T
A
K
K
Site 18
T125
P
G
L
S
I
G
D
T
A
K
K
L
G
E
M
Site 19
S134
K
K
L
G
E
M
W
S
E
Q
S
A
K
D
K
Site 20
S137
G
E
M
W
S
E
Q
S
A
K
D
K
Q
P
Y
Site 21
Y155
A
A
K
L
K
E
K
Y
E
K
D
I
A
A
Y
Site 22
Y162
Y
E
K
D
I
A
A
Y
R
A
K
G
K
S
E
Site 23
S168
A
Y
R
A
K
G
K
S
E
A
G
K
K
G
P
Site 24
T179
K
K
G
P
G
R
P
T
G
S
K
K
K
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation