PhosphoNET

           
Protein Info 
   
Short Name:  PTBP1
Full Name:  Polypyrimidine tract-binding protein 1
Alias:  Heterogeneous nuclear ribonucleoprotein I; Heterogeneous nuclear ribonucleoprotein I;hnRNP I;57 kDa RNA-binding protein PPTB-1; HnRNP-I; PTB
Type:  RNA binding protein
Mass (Da):  57221
Number AA:  531
UniProt ID:  P26599
International Prot ID:  IPI00179964
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030530  GO:0005730  GO:0005654 Uniprot OncoNet
Molecular Function:  GO:0000166  GO:0008187  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0000398  GO:0008380   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T12VPDIAVGTKRGSDEL
Site 2S16AVGTKRGSDELFSTC
Site 3S21RGSDELFSTCVTNGP
Site 4T22GSDELFSTCVTNGPF
Site 5S33NGPFIMSSNSASAAN
Site 6S35PFIMSSNSASAANGN
Site 7S37IMSSNSASAANGNDS
Site 8S44SAANGNDSKKFKGDS
Site 9S51SKKFKGDSRSAGVPS
Site 10S53KFKGDSRSAGVPSRV
Site 11T109NTEEAANTMVNYYTS
Site 12T118VNYYTSVTPVLRGQP
Site 13Y127VLRGQPIYIQFSNHK
Site 14S131QPIYIQFSNHKELKT
Site 15T138SNHKELKTDSSPNQA
Site 16S140HKELKTDSSPNQARA
Site 17S141KELKTDSSPNQARAQ
Site 18Y193IIVENLFYPVTLDVL
Site 19Y228QFQALLQYADPVSAQ
Site 20S233LQYADPVSAQHAKLS
Site 21S240SAQHAKLSLDGQNIY
Site 22Y247SLDGQNIYNACCTLR
Site 23S262IDFSKLTSLNVKYNN
Site 24Y267LTSLNVKYNNDKSRD
Site 25S272VKYNNDKSRDYTRPD
Site 26Y275NNDKSRDYTRPDLPS
Site 27T276NDKSRDYTRPDLPSG
Site 28S282YTRPDLPSGDSQPSL
Site 29S285PDLPSGDSQPSLDQT
Site 30S288PSGDSQPSLDQTMAA
Site 31T350NLNPERVTPQSLFIL
Site 32T407HGKPIRITLSKHQNV
Site 33T427GQEDQGLTKDYGNSP
Site 34Y430DQGLTKDYGNSPLHR
Site 35S433LTKDYGNSPLHRFKK
Site 36S443HRFKKPGSKNFQNIF
Site 37S453FQNIFPPSATLHLSN
Site 38S459PSATLHLSNIPPSVS
Site 39S464HLSNIPPSVSEEDLK
Site 40S466SNIPPSVSEEDLKVL
Site 41S525ENHHLRVSFSKSTI_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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