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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MSP
Full Name:
Hepatocyte growth factor-like protein
Alias:
D3F15S2; DNF15S2; HGFL; Macrophage stimulating 1; MST1
Type:
Extracellular region protein
Mass (Da):
80320
Number AA:
711
UniProt ID:
P26927
International Prot ID:
IPI00292218
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
G
V
P
G
Q
R
S
P
L
N
D
F
Q
V
Site 2
T32
D
F
Q
V
L
R
G
T
E
L
Q
H
L
L
H
Site 3
T84
G
C
Q
L
L
P
W
T
Q
H
S
P
H
T
R
Site 4
S87
L
L
P
W
T
Q
H
S
P
H
T
R
L
R
R
Site 5
T90
W
T
Q
H
S
P
H
T
R
L
R
R
S
G
R
Site 6
S95
P
H
T
R
L
R
R
S
G
R
C
D
L
F
Q
Site 7
Y106
D
L
F
Q
K
K
D
Y
V
R
T
C
I
M
N
Site 8
T121
N
G
V
G
Y
R
G
T
M
A
T
T
V
G
G
Site 9
T125
Y
R
G
T
M
A
T
T
V
G
G
L
P
C
Q
Site 10
Y144
K
F
P
N
D
H
K
Y
T
P
T
L
R
N
G
Site 11
T145
F
P
N
D
H
K
Y
T
P
T
L
R
N
G
L
Site 12
T147
N
D
H
K
Y
T
P
T
L
R
N
G
L
E
E
Site 13
S180
D
P
A
V
R
F
Q
S
C
G
I
K
S
C
R
Site 14
T206
Y
R
G
A
V
D
R
T
E
S
G
R
E
C
Q
Site 15
S208
G
A
V
D
R
T
E
S
G
R
E
C
Q
R
W
Site 16
Y239
D
Q
G
L
D
D
N
Y
C
R
N
P
D
G
S
Site 17
S270
C
D
L
P
R
C
G
S
E
A
Q
P
R
Q
E
Site 18
T280
Q
P
R
Q
E
A
T
T
V
S
C
F
R
G
K
Site 19
S282
R
Q
E
A
T
T
V
S
C
F
R
G
K
G
E
Site 20
T294
K
G
E
G
Y
R
G
T
A
N
T
T
T
A
G
Site 21
T297
G
Y
R
G
T
A
N
T
T
T
A
G
V
P
C
Site 22
T318
I
P
H
Q
H
R
F
T
P
E
K
Y
A
C
K
Site 23
Y322
H
R
F
T
P
E
K
Y
A
C
K
D
L
R
E
Site 24
T345
S
E
A
P
W
C
F
T
L
R
P
G
M
R
A
Site 25
Y371
D
V
R
P
Q
D
C
Y
H
G
A
G
E
Q
Y
Site 26
T381
A
G
E
Q
Y
R
G
T
V
S
K
T
R
K
G
Site 27
S383
E
Q
Y
R
G
T
V
S
K
T
R
K
G
V
Q
Site 28
T398
C
Q
R
W
S
A
E
T
P
H
K
P
Q
F
T
Site 29
T405
T
P
H
K
P
Q
F
T
F
T
S
E
P
H
A
Site 30
Y442
D
P
R
T
P
F
D
Y
C
A
L
R
R
C
A
Site 31
S455
C
A
D
D
Q
P
P
S
I
L
D
P
P
D
Q
Site 32
S480
D
R
L
D
Q
R
R
S
K
L
R
V
V
G
G
Site 33
S492
V
G
G
H
P
G
N
S
P
W
T
V
S
L
R
Site 34
T495
H
P
G
N
S
P
W
T
V
S
L
R
N
R
Q
Site 35
S497
G
N
S
P
W
T
V
S
L
R
N
R
Q
G
Q
Site 36
T519
V
K
E
Q
W
I
L
T
A
R
Q
C
F
S
S
Site 37
S551
N
P
Q
H
G
E
P
S
L
Q
R
V
P
V
A
Site 38
T579
L
K
L
E
R
S
V
T
L
N
Q
R
V
A
L
Site 39
T613
G
W
G
E
T
K
G
T
G
N
D
T
V
L
N
Site 40
S643
H
R
G
R
V
R
E
S
E
M
C
T
E
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation