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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPP4
Full Name:
Dipeptidyl peptidase 4
Alias:
ADABP; ADCP2; Adenosine deaminase complexing 2; CD26; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; Dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing 2); DPP IV; DPPIV; EC 3.4.14.5; T-cell activation antigen CD26; TP103
Type:
Extracellular region, Intercellular canaliculus, Plasma membrane, Cell surface, Integral membrane protein
Mass (Da):
88279
Number AA:
766
UniProt ID:
P27487
International Prot ID:
IPI00018953
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016324
GO:0009986
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004177
GO:0008239
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0042110
GO:0006508
GO:0033632
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T44
A
D
S
R
K
T
Y
T
L
T
D
Y
L
K
N
Site 2
T52
L
T
D
Y
L
K
N
T
Y
R
L
K
L
Y
S
Site 3
Y381
I
I
S
N
E
E
G
Y
R
H
I
C
Y
F
Q
Site 4
Y386
E
G
Y
R
H
I
C
Y
F
Q
I
D
K
K
D
Site 5
Y456
L
N
P
E
R
C
Q
Y
Y
S
V
S
F
S
K
Site 6
Y457
N
P
E
R
C
Q
Y
Y
S
V
S
F
S
K
E
Site 7
S460
R
C
Q
Y
Y
S
V
S
F
S
K
E
A
K
Y
Site 8
T481
G
P
G
L
P
L
Y
T
L
H
S
S
V
N
D
Site 9
S484
L
P
L
Y
T
L
H
S
S
V
N
D
K
G
L
Site 10
S485
P
L
Y
T
L
H
S
S
V
N
D
K
G
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation