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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
dCK
Full Name:
Deoxycytidine kinase
Alias:
EC 2.7.1.74
Type:
Kinase (non-protein); Nucleotide Metabolism - pyrimidine; EC 2.7.1.74; Nucleotide Metabolism - purine
Mass (Da):
30519
Number AA:
260
UniProt ID:
P27707
International Prot ID:
IPI00020454
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004137
GO:0016773
PhosphoSite+
KinaseNET
Biological Process:
GO:0006220
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
A
T
P
P
K
R
S
C
P
Site 2
S8
M
A
T
P
P
K
R
S
C
P
S
F
S
A
S
Site 3
S11
P
P
K
R
S
C
P
S
F
S
A
S
S
E
G
Site 4
S13
K
R
S
C
P
S
F
S
A
S
S
E
G
T
R
Site 5
S15
S
C
P
S
F
S
A
S
S
E
G
T
R
I
K
Site 6
S16
C
P
S
F
S
A
S
S
E
G
T
R
I
K
K
Site 7
T19
F
S
A
S
S
E
G
T
R
I
K
K
I
S
I
Site 8
S25
G
T
R
I
K
K
I
S
I
E
G
N
I
A
A
Site 9
S35
G
N
I
A
A
G
K
S
T
F
V
N
I
L
K
Site 10
S63
A
R
W
C
N
V
Q
S
T
Q
D
E
F
E
E
Site 11
T64
R
W
C
N
V
Q
S
T
Q
D
E
F
E
E
L
Site 12
T72
Q
D
E
F
E
E
L
T
M
S
Q
K
N
G
G
Site 13
S74
E
F
E
E
L
T
M
S
Q
K
N
G
G
N
V
Site 14
Y86
G
N
V
L
Q
M
M
Y
E
K
P
E
R
W
S
Site 15
Y99
W
S
F
T
F
Q
T
Y
A
C
L
S
R
I
R
Site 16
S111
R
I
R
A
Q
L
A
S
L
N
G
K
L
K
D
Site 17
S129
P
V
L
F
F
E
R
S
V
Y
S
D
R
Y
I
Site 18
S132
F
F
E
R
S
V
Y
S
D
R
Y
I
F
A
S
Site 19
Y135
R
S
V
Y
S
D
R
Y
I
F
A
S
N
L
Y
Site 20
S139
S
D
R
Y
I
F
A
S
N
L
Y
E
S
E
C
Site 21
Y142
Y
I
F
A
S
N
L
Y
E
S
E
C
M
N
E
Site 22
Y190
E
T
C
L
H
R
I
Y
L
R
G
R
N
E
E
Site 23
Y204
E
Q
G
I
P
L
E
Y
L
E
K
L
H
Y
K
Site 24
Y210
E
Y
L
E
K
L
H
Y
K
H
E
S
W
L
L
Site 25
T223
L
L
H
R
T
L
K
T
N
F
D
Y
L
Q
E
Site 26
Y246
N
E
D
F
K
D
K
Y
E
S
L
V
E
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation