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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
calreticulin
Full Name:
Calreticulin
Alias:
Autoantigen Ro; CALR; Calreticulin); CC1qR; CRP55; CRT; CRTC; ERp60; FLJ26680; Grp60; HACBP; RO; Sicca syndrome antigen A (autoantigen Ro; SSA
Type:
Co-regulator for nuclear receptor, Calcium-binding protein
Mass (Da):
48142
Number AA:
417
UniProt ID:
P27797
International Prot ID:
IPI00020599
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042824
GO:0005829
GO:0005788
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0050681
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
GO:0042921
GO:0045665
Phosida
TranscriptoNet
STRING
Kinexus Products
Calreticulin pan-specific antibody AB-NN137-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN137-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
A
V
A
E
P
A
V
Y
F
K
E
Q
F
L
D
Site 2
T34
F
L
D
G
D
G
W
T
S
R
W
I
E
S
K
Site 3
S44
W
I
E
S
K
H
K
S
D
F
G
K
F
V
L
Site 4
S52
D
F
G
K
F
V
L
S
S
G
K
F
Y
G
D
Site 5
S53
F
G
K
F
V
L
S
S
G
K
F
Y
G
D
E
Site 6
Y57
V
L
S
S
G
K
F
Y
G
D
E
E
K
D
K
Site 7
S69
K
D
K
G
L
Q
T
S
Q
D
A
R
F
Y
A
Site 8
Y75
T
S
Q
D
A
R
F
Y
A
L
S
A
S
F
E
Site 9
S78
D
A
R
F
Y
A
L
S
A
S
F
E
P
F
S
Site 10
S80
R
F
Y
A
L
S
A
S
F
E
P
F
S
N
K
Site 11
S85
S
A
S
F
E
P
F
S
N
K
G
Q
T
L
V
Site 12
Y109
N
I
D
C
G
G
G
Y
V
K
L
F
P
N
S
Site 13
S116
Y
V
K
L
F
P
N
S
L
D
Q
T
D
M
H
Site 14
T120
F
P
N
S
L
D
Q
T
D
M
H
G
D
S
E
Site 15
Y128
D
M
H
G
D
S
E
Y
N
I
M
F
G
P
D
Site 16
Y150
K
V
H
V
I
F
N
Y
K
G
K
N
V
L
I
Site 17
T169
R
C
K
D
D
E
F
T
H
L
Y
T
L
I
V
Site 18
Y172
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Site 19
T173
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
N
Site 20
T181
L
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
Site 21
Y182
I
V
R
P
D
N
T
Y
E
V
K
I
D
N
S
Site 22
S189
Y
E
V
K
I
D
N
S
Q
V
E
S
G
S
L
Site 23
S193
I
D
N
S
Q
V
E
S
G
S
L
E
D
D
W
Site 24
S195
N
S
Q
V
E
S
G
S
L
E
D
D
W
D
F
Site 25
T229
R
A
K
I
D
D
P
T
D
S
K
P
E
D
W
Site 26
S231
K
I
D
D
P
T
D
S
K
P
E
D
W
D
K
Site 27
Y271
P
V
I
Q
N
P
E
Y
K
G
E
W
K
P
R
Site 28
Y285
R
Q
I
D
N
P
D
Y
K
G
T
W
I
H
P
Site 29
Y299
P
E
I
D
N
P
E
Y
S
P
D
P
S
I
Y
Site 30
S300
E
I
D
N
P
E
Y
S
P
D
P
S
I
Y
A
Site 31
S304
P
E
Y
S
P
D
P
S
I
Y
A
Y
D
N
F
Site 32
Y306
Y
S
P
D
P
S
I
Y
A
Y
D
N
F
G
V
Site 33
Y308
P
D
P
S
I
Y
A
Y
D
N
F
G
V
L
G
Site 34
Y338
L
I
T
N
D
E
A
Y
A
E
E
F
G
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation