PhosphoNET

           
Protein Info 
   
Short Name:  HLA-DMB
Full Name:  HLA class II histocompatibility antigen, DM beta chain
Alias:  2DMB; Class II histocompatibility antigen, M beta chain; D6S221E; DMB; HLA class II histocompatibility antigen, DM beta; Major histocompatibility complex, class II, DM beta; MHC class II antigen DMB; MHC class II antigen HLA-DM beta chain; MHC class II HLA-DMB; RING7
Type:  Vesicle protein
Mass (Da):  28943
Number AA:  263
UniProt ID:  P28068
International Prot ID:  IPI00000793
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0042613  GO:0005768  GO:0016021 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0002504  GO:0006955   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T36CLLDDAGTPKDFTYC
Site 2T41AGTPKDFTYCISFNK
Site 3Y42GTPKDFTYCISFNKD
Site 4T52SFNKDLLTCWDPEEN
Site 5S77NSLANVLSQHLNQKD
Site 6T85QHLNQKDTLMQRLRN
Site 7T101LQNCATHTQPFWGSL
Site 8S107HTQPFWGSLTNRTRP
Site 9T109QPFWGSLTNRTRPPS
Site 10T112WGSLTNRTRPPSVQV
Site 11S116TNRTRPPSVQVAKTT
Site 12T123SVQVAKTTPFNTREP
Site 13T148YPAEVTITWRKNGKL
Site 14S160GKLVMPHSSAHKTAQ
Site 15T165PHSSAHKTAQPNGDW
Site 16T173AQPNGDWTYQTLSHL
Site 17Y174QPNGDWTYQTLSHLA
Site 18T176NGDWTYQTLSHLALT
Site 19S178DWTYQTLSHLALTPS
Site 20T183TLSHLALTPSYGDTY
Site 21S185SHLALTPSYGDTYTC
Site 22T189LTPSYGDTYTCVVEH
Site 23Y190TPSYGDTYTCVVEHI
Site 24T191PSYGDTYTCVVEHIG
Site 25T208EPILRDWTPGLSPMQ
Site 26S212RDWTPGLSPMQTLKV
Site 27S246SWRRAGHSSYTPLPG
Site 28S247WRRAGHSSYTPLPGS
Site 29Y248RRAGHSSYTPLPGSN
Site 30T249RAGHSSYTPLPGSNY
Site 31S254SYTPLPGSNYSEGWH
Site 32Y256TPLPGSNYSEGWHIS
Site 33S257PLPGSNYSEGWHIS_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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