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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Hoxd10
Full Name:
Homeobox protein Hox-D10
Alias:
Homeobox d10; Hox4; Hox-4.4; Hox4d; Hox4e
Type:
Nucleus protein
Mass (Da):
38411
Number AA:
340
UniProt ID:
P28358
International Prot ID:
IPI00292735
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
F
P
N
S
S
P
A
A
N
T
F
L
Site 2
S24
S
L
I
S
A
C
R
S
D
S
F
Y
S
S
S
Site 3
S26
I
S
A
C
R
S
D
S
F
Y
S
S
S
A
S
Site 4
Y28
A
C
R
S
D
S
F
Y
S
S
S
A
S
M
Y
Site 5
S29
C
R
S
D
S
F
Y
S
S
S
A
S
M
Y
M
Site 6
S30
R
S
D
S
F
Y
S
S
S
A
S
M
Y
M
P
Site 7
S31
S
D
S
F
Y
S
S
S
A
S
M
Y
M
P
P
Site 8
S33
S
F
Y
S
S
S
A
S
M
Y
M
P
P
P
S
Site 9
Y35
Y
S
S
S
A
S
M
Y
M
P
P
P
S
A
D
Site 10
S40
S
M
Y
M
P
P
P
S
A
D
M
G
T
Y
G
Site 11
T45
P
P
S
A
D
M
G
T
Y
G
M
Q
T
C
G
Site 12
S56
Q
T
C
G
L
L
P
S
L
A
K
R
E
V
N
Site 13
S80
P
Y
I
P
Q
V
D
S
W
T
D
P
N
R
S
Site 14
T82
I
P
Q
V
D
S
W
T
D
P
N
R
S
C
R
Site 15
S87
S
W
T
D
P
N
R
S
C
R
I
E
Q
P
V
Site 16
T95
C
R
I
E
Q
P
V
T
Q
Q
V
P
T
C
S
Site 17
S102
T
Q
Q
V
P
T
C
S
F
T
T
N
I
K
E
Site 18
S125
D
K
R
N
K
L
I
S
A
E
V
P
S
Y
Q
Site 19
Y131
I
S
A
E
V
P
S
Y
Q
R
L
V
P
E
S
Site 20
S138
Y
Q
R
L
V
P
E
S
C
P
V
E
N
P
E
Site 21
Y151
P
E
V
P
V
P
G
Y
F
R
L
S
Q
T
Y
Site 22
S155
V
P
G
Y
F
R
L
S
Q
T
Y
A
T
G
K
Site 23
Y166
A
T
G
K
T
Q
E
Y
N
N
S
P
E
G
S
Site 24
S169
K
T
Q
E
Y
N
N
S
P
E
G
S
S
T
V
Site 25
S173
Y
N
N
S
P
E
G
S
S
T
V
M
L
Q
L
Site 26
T175
N
S
P
E
G
S
S
T
V
M
L
Q
L
N
P
Site 27
S191
G
A
A
K
P
Q
L
S
A
A
Q
L
Q
M
E
Site 28
S206
K
K
M
N
E
P
V
S
G
Q
E
P
T
K
V
Site 29
T211
P
V
S
G
Q
E
P
T
K
V
S
Q
V
E
S
Site 30
S214
G
Q
E
P
T
K
V
S
Q
V
E
S
P
E
A
Site 31
S218
T
K
V
S
Q
V
E
S
P
E
A
K
G
G
L
Site 32
S230
G
G
L
P
E
E
R
S
C
L
A
E
V
S
V
Site 33
S236
R
S
C
L
A
E
V
S
V
S
S
P
E
V
Q
Site 34
S238
C
L
A
E
V
S
V
S
S
P
E
V
Q
E
K
Site 35
S239
L
A
E
V
S
V
S
S
P
E
V
Q
E
K
E
Site 36
S253
E
S
K
E
E
I
K
S
D
T
P
T
S
N
W
Site 37
T255
K
E
E
I
K
S
D
T
P
T
S
N
W
L
T
Site 38
T257
E
I
K
S
D
T
P
T
S
N
W
L
T
A
K
Site 39
S258
I
K
S
D
T
P
T
S
N
W
L
T
A
K
S
Site 40
T262
T
P
T
S
N
W
L
T
A
K
S
G
R
K
K
Site 41
S265
S
N
W
L
T
A
K
S
G
R
K
K
R
C
P
Site 42
Y273
G
R
K
K
R
C
P
Y
T
K
H
Q
T
L
E
Site 43
T274
R
K
K
R
C
P
Y
T
K
H
Q
T
L
E
L
Site 44
Y290
K
E
F
L
F
N
M
Y
L
T
R
E
R
R
L
Site 45
T292
F
L
F
N
M
Y
L
T
R
E
R
R
L
E
I
Site 46
S300
R
E
R
R
L
E
I
S
K
S
V
N
L
T
D
Site 47
S302
R
R
L
E
I
S
K
S
V
N
L
T
D
R
Q
Site 48
T306
I
S
K
S
V
N
L
T
D
R
Q
V
K
I
W
Site 49
T334
E
N
R
I
R
E
L
T
A
N
L
T
F
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation