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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HTR1E
Full Name:
5-hydroxytryptamine receptor 1E
Alias:
S31;Serotonin receptor 1E
Type:
Mass (Da):
41682
Number AA:
365
UniProt ID:
P28566
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T49
A
V
I
M
A
I
G
T
T
K
K
L
H
Q
P
Site 2
T50
V
I
M
A
I
G
T
T
K
K
L
H
Q
P
A
Site 3
T125
L
D
R
Y
W
A
I
T
N
A
I
E
Y
A
R
Site 4
Y130
A
I
T
N
A
I
E
Y
A
R
K
R
T
A
K
Site 5
T135
I
E
Y
A
R
K
R
T
A
K
R
A
A
L
M
Site 6
S162
M
P
P
L
F
W
R
S
H
R
R
L
S
P
P
Site 7
S167
W
R
S
H
R
R
L
S
P
P
P
S
Q
C
T
Site 8
S171
R
R
L
S
P
P
P
S
Q
C
T
I
Q
H
D
Site 9
S211
R
I
Y
H
A
A
K
S
L
Y
Q
K
R
G
S
Site 10
Y213
Y
H
A
A
K
S
L
Y
Q
K
R
G
S
S
R
Site 11
S218
S
L
Y
Q
K
R
G
S
S
R
H
L
S
N
R
Site 12
S219
L
Y
Q
K
R
G
S
S
R
H
L
S
N
R
S
Site 13
S223
R
G
S
S
R
H
L
S
N
R
S
T
D
S
Q
Site 14
S226
S
R
H
L
S
N
R
S
T
D
S
Q
N
S
F
Site 15
T227
R
H
L
S
N
R
S
T
D
S
Q
N
S
F
A
Site 16
S229
L
S
N
R
S
T
D
S
Q
N
S
F
A
S
C
Site 17
S232
R
S
T
D
S
Q
N
S
F
A
S
C
K
L
T
Site 18
S245
L
T
Q
T
F
C
V
S
D
F
S
T
S
D
P
Site 19
S248
T
F
C
V
S
D
F
S
T
S
D
P
T
T
E
Site 20
T249
F
C
V
S
D
F
S
T
S
D
P
T
T
E
F
Site 21
T253
D
F
S
T
S
D
P
T
T
E
F
E
K
F
H
Site 22
T254
F
S
T
S
D
P
T
T
E
F
E
K
F
H
A
Site 23
S262
E
F
E
K
F
H
A
S
I
R
I
P
P
F
D
Site 24
S282
P
G
E
R
Q
Q
I
S
S
T
R
E
R
K
A
Site 25
S283
G
E
R
Q
Q
I
S
S
T
R
E
R
K
A
A
Site 26
S346
I
N
P
L
L
Y
T
S
F
N
E
D
F
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation