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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GRN
Full Name:
Granulins
Alias:
Proepithelin
Type:
Mass (Da):
63526
Number AA:
593
UniProt ID:
P28799
International Prot ID:
IPI00296713
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005615
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005102
GO:0005125
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0001835
GO:0007154
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Granulin (Q539-G562, human) biotinylated peptide - Powder PE-03AAN95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-03AAN95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
W
T
L
V
S
W
V
A
L
T
A
G
Site 2
T11
L
V
S
W
V
A
L
T
A
G
L
V
A
G
T
Site 3
S38
C
L
D
P
G
G
A
S
Y
S
C
C
R
P
L
Site 4
S40
D
P
G
G
A
S
Y
S
C
C
R
P
L
L
D
Site 5
T52
L
L
D
K
W
P
T
T
L
S
R
H
L
G
G
Site 6
S54
D
K
W
P
T
T
L
S
R
H
L
G
G
P
C
Site 7
S116
G
R
S
C
F
Q
R
S
G
N
N
S
V
G
A
Site 8
S120
F
Q
R
S
G
N
N
S
V
G
A
I
Q
C
P
Site 9
T182
H
T
R
C
I
T
P
T
G
T
H
P
L
A
K
Site 10
T196
K
K
L
P
A
Q
R
T
N
R
A
V
A
L
S
Site 11
S213
V
M
C
P
D
A
R
S
R
C
P
D
G
S
T
Site 12
S219
R
S
R
C
P
D
G
S
T
C
C
E
L
P
S
Site 13
T220
S
R
C
P
D
G
S
T
C
C
E
L
P
S
G
Site 14
Y229
C
E
L
P
S
G
K
Y
G
C
C
P
M
P
N
Site 15
S262
L
I
Q
S
K
C
L
S
K
E
N
A
T
T
D
Site 16
T268
L
S
K
E
N
A
T
T
D
L
L
T
K
L
P
Site 17
Y294
E
V
S
C
P
D
G
Y
T
C
C
R
L
Q
S
Site 18
T295
V
S
C
P
D
G
Y
T
C
C
R
L
Q
S
G
Site 19
T330
P
A
G
F
T
C
D
T
Q
K
G
T
C
E
Q
Site 20
S353
E
K
A
P
A
H
L
S
L
P
D
P
Q
A
L
Site 21
S370
D
V
P
C
D
N
V
S
S
C
P
S
S
D
T
Site 22
S371
V
P
C
D
N
V
S
S
C
P
S
S
D
T
C
Site 23
S374
D
N
V
S
S
C
P
S
S
D
T
C
C
Q
L
Site 24
S375
N
V
S
S
C
P
S
S
D
T
C
C
Q
L
T
Site 25
T377
S
S
C
P
S
S
D
T
C
C
Q
L
T
S
G
Site 26
S420
E
G
Q
C
Q
R
G
S
E
I
V
A
G
L
E
Site 27
S435
K
M
P
A
R
R
A
S
L
S
H
P
R
D
I
Site 28
S437
P
A
R
R
A
S
L
S
H
P
R
D
I
G
C
Site 29
T448
D
I
G
C
D
Q
H
T
S
C
P
V
G
Q
T
Site 30
S511
P
A
T
F
L
A
R
S
P
H
V
G
V
K
D
Site 31
T570
F
R
C
A
A
R
G
T
K
C
L
R
R
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation