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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTGF
Full Name:
Connective tissue growth factor
Alias:
CCN2; HCS24; Hypertrophic chondrocyte-specific 24; IGFBP8; NOV2
Type:
Adhesion
Mass (Da):
38091
Number AA:
349
UniProt ID:
P29279
International Prot ID:
IPI00020977
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0008201
GO:0005520
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0008544
GO:0001558
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T69
K
Q
L
G
E
L
C
T
E
R
D
P
C
D
P
Site 2
S86
G
L
F
C
H
F
G
S
P
A
N
R
K
I
G
Site 3
T108
A
P
C
I
F
G
G
T
V
Y
R
S
G
E
S
Site 4
Y110
C
I
F
G
G
T
V
Y
R
S
G
E
S
F
Q
Site 5
S112
F
G
G
T
V
Y
R
S
G
E
S
F
Q
S
S
Site 6
S115
T
V
Y
R
S
G
E
S
F
Q
S
S
C
K
Y
Site 7
S118
R
S
G
E
S
F
Q
S
S
C
K
Y
Q
C
T
Site 8
Y122
S
F
Q
S
S
C
K
Y
Q
C
T
C
L
D
G
Site 9
S145
S
M
D
V
R
L
P
S
P
D
C
P
F
P
R
Site 10
T173
C
D
E
P
K
D
Q
T
V
V
G
P
A
L
A
Site 11
T187
A
A
Y
R
L
E
D
T
F
G
P
D
P
T
M
Site 12
T193
D
T
F
G
P
D
P
T
M
I
R
A
N
C
L
Site 13
T203
R
A
N
C
L
V
Q
T
T
E
W
S
A
C
S
Site 14
T222
M
G
I
S
T
R
V
T
N
D
N
A
S
C
R
Site 15
S227
R
V
T
N
D
N
A
S
C
R
L
E
K
Q
S
Site 16
S234
S
C
R
L
E
K
Q
S
R
L
C
M
V
R
P
Site 17
T259
K
G
K
K
C
I
R
T
P
K
I
S
K
P
I
Site 18
S263
C
I
R
T
P
K
I
S
K
P
I
K
F
E
L
Site 19
S271
K
P
I
K
F
E
L
S
G
C
T
S
M
K
T
Site 20
S275
F
E
L
S
G
C
T
S
M
K
T
Y
R
A
K
Site 21
Y279
G
C
T
S
M
K
T
Y
R
A
K
F
C
G
V
Site 22
T294
C
T
D
G
R
C
C
T
P
H
R
T
T
T
L
Site 23
T299
C
C
T
P
H
R
T
T
T
L
P
V
E
F
K
Site 24
T300
C
T
P
H
R
T
T
T
L
P
V
E
F
K
C
Site 25
Y340
N
D
I
F
E
S
L
Y
Y
R
K
M
Y
G
D
Site 26
Y341
D
I
F
E
S
L
Y
Y
R
K
M
Y
G
D
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation