PhosphoNET

           
Protein Info 
   
Short Name:  MPG
Full Name:  DNA-3-methyladenine glycosylase
Alias:  3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; 3MG; AAG; ADPG; alkyladenine DNA glycosylase; ANPG; MDG; MID1; N-methylpurine- DNA glycosirase; N-methylpurine-DNA glycosylase
Type:  Hydrolase; EC 3.2.2.21
Mass (Da):  32869
Number AA:  298
UniProt ID:  P29372
International Prot ID:  IPI00295497
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005654  GO:0005654  GO:0005737 Uniprot OncoNet
Molecular Function:  GO:0003905  GO:0003684  GO:0042802 PhosphoSite+ KinaseNET
Biological Process:  GO:0006307  GO:0045007  GO:0006195 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S33ARAGQPHSSSDAAQA
Site 2S35AGQPHSSSDAAQAPA
Site 3S47APAEQPHSSSDAAQA
Site 4T66ERCLGPPTTPGPYRS
Site 5T67RCLGPPTTPGPYRSI
Site 6Y71PPTTPGPYRSIYFSS
Site 7S73TTPGPYRSIYFSSPK
Site 8Y75PGPYRSIYFSSPKGH
Site 9S77PYRSIYFSSPKGHLT
Site 10S78YRSIYFSSPKGHLTR
Site 11T84SSPKGHLTRLGLEFF
Site 12T115VRRLPNGTELRGRIV
Site 13Y127RIVETEAYLGPEDEA
Site 14S137PEDEAAHSRGGRQTP
Site 15T143HSRGGRQTPRNRGMF
Site 16T192EPLEGLETMRQLRST
Site 17S198ETMRQLRSTLRKGTA
Site 18T199TMRQLRSTLRKGTAS
Site 19T204RSTLRKGTASRVLKD
Site 20S206TLRKGTASRVLKDRE
Site 21S216LKDRELCSGPSKLCQ
Site 22S230QALAINKSFDQRDLA
Site 23S252ERGPLEPSEPAVVAA
Site 24Y278ARKPLRFYVRGSPWV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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