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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARID4A
Full Name:
AT-rich interactive domain-containing protein 4A
Alias:
ARID domain-containing protein 4A
Type:
Adaptor/scaffold
Mass (Da):
142752
Number AA:
1257
UniProt ID:
P29374
International Prot ID:
IPI00296069
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0017053
Uniprot
OncoNet
Molecular Function:
GO:0003682
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006333
GO:0045892
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
K
A
A
D
E
P
A
Y
L
T
V
G
T
D
V
Site 2
Y20
G
T
D
V
S
A
K
Y
R
G
A
F
C
E
A
Site 3
T47
V
L
L
K
Q
D
N
T
T
Q
L
V
Q
D
D
Site 4
S71
A
I
V
E
T
R
T
S
D
G
S
F
Q
E
A
Site 5
S74
E
T
R
T
S
D
G
S
F
Q
E
A
I
I
S
Site 6
S81
S
F
Q
E
A
I
I
S
K
L
T
D
A
S
W
Site 7
Y89
K
L
T
D
A
S
W
Y
T
V
V
F
D
D
G
Site 8
T90
L
T
D
A
S
W
Y
T
V
V
F
D
D
G
D
Site 9
T100
F
D
D
G
D
E
R
T
L
R
R
T
S
L
C
Site 10
T104
D
E
R
T
L
R
R
T
S
L
C
L
K
G
E
Site 11
S105
E
R
T
L
R
R
T
S
L
C
L
K
G
E
R
Site 12
S117
G
E
R
H
F
A
E
S
E
T
L
D
Q
L
P
Site 13
T126
T
L
D
Q
L
P
L
T
N
P
E
H
F
G
T
Site 14
T133
T
N
P
E
H
F
G
T
P
V
I
A
K
K
T
Site 15
T140
T
P
V
I
A
K
K
T
N
R
G
R
R
S
S
Site 16
S146
K
T
N
R
G
R
R
S
S
L
P
V
T
E
D
Site 17
S147
T
N
R
G
R
R
S
S
L
P
V
T
E
D
E
Site 18
T151
R
R
S
S
L
P
V
T
E
D
E
K
E
E
E
Site 19
S159
E
D
E
K
E
E
E
S
S
E
E
E
D
E
D
Site 20
S160
D
E
K
E
E
E
S
S
E
E
E
D
E
D
K
Site 21
Y191
A
T
E
R
T
E
W
Y
P
A
L
V
I
S
P
Site 22
T205
P
S
C
N
D
D
I
T
V
K
K
D
Q
C
L
Site 23
S215
K
D
Q
C
L
V
R
S
F
I
D
S
K
F
Y
Site 24
S223
F
I
D
S
K
F
Y
S
I
A
R
K
D
I
K
Site 25
S240
D
I
L
N
L
P
E
S
E
L
S
T
K
P
G
Site 26
S243
N
L
P
E
S
E
L
S
T
K
P
G
L
Q
K
Site 27
T244
L
P
E
S
E
L
S
T
K
P
G
L
Q
K
A
Site 28
S269
D
N
W
K
M
D
I
S
E
I
L
E
S
S
S
Site 29
S274
D
I
S
E
I
L
E
S
S
S
S
D
D
E
D
Site 30
S276
S
E
I
L
E
S
S
S
S
D
D
E
D
G
P
Site 31
S277
E
I
L
E
S
S
S
S
D
D
E
D
G
P
A
Site 32
T298
K
E
K
E
A
K
K
T
E
E
E
V
P
E
E
Site 33
T328
K
F
M
E
D
R
G
T
P
I
N
K
P
P
V
Site 34
Y351
F
K
L
F
R
L
V
Y
H
Q
G
G
C
D
N
Site 35
Y369
G
A
V
W
K
Q
I
Y
M
D
L
G
I
P
I
Site 36
S382
P
I
L
N
S
A
A
S
Y
N
V
K
T
A
Y
Site 37
T387
A
A
S
Y
N
V
K
T
A
Y
R
K
Y
L
Y
Site 38
Y389
S
Y
N
V
K
T
A
Y
R
K
Y
L
Y
G
F
Site 39
Y392
V
K
T
A
Y
R
K
Y
L
Y
G
F
E
E
Y
Site 40
Y394
T
A
Y
R
K
Y
L
Y
G
F
E
E
Y
C
R
Site 41
Y399
Y
L
Y
G
F
E
E
Y
C
R
S
A
N
I
Q
Site 42
T409
S
A
N
I
Q
F
R
T
V
H
H
H
E
P
K
Site 43
S427
E
K
K
D
L
E
E
S
M
E
E
A
L
K
L
Site 44
T441
L
D
Q
E
M
P
L
T
E
V
K
S
E
P
E
Site 45
S445
M
P
L
T
E
V
K
S
E
P
E
E
N
I
D
Site 46
S453
E
P
E
E
N
I
D
S
N
S
E
S
E
R
E
Site 47
S455
E
E
N
I
D
S
N
S
E
S
E
R
E
E
I
Site 48
S457
N
I
D
S
N
S
E
S
E
R
E
E
I
E
L
Site 49
S466
R
E
E
I
E
L
K
S
P
R
G
R
R
R
I
Site 50
S479
R
I
A
R
D
V
N
S
I
K
K
E
I
E
E
Site 51
T489
K
E
I
E
E
E
K
T
E
D
K
L
K
D
N
Site 52
T498
D
K
L
K
D
N
D
T
E
N
K
D
V
D
D
Site 53
Y507
N
K
D
V
D
D
D
Y
E
T
A
E
K
K
E
Site 54
T509
D
V
D
D
D
Y
E
T
A
E
K
K
E
N
E
Site 55
T524
L
L
L
G
R
K
N
T
P
K
Q
K
E
K
K
Site 56
S538
K
I
K
K
Q
E
D
S
D
K
D
S
D
E
E
Site 57
S542
Q
E
D
S
D
K
D
S
D
E
E
E
E
K
S
Site 58
S549
S
D
E
E
E
E
K
S
Q
E
R
E
E
T
E
Site 59
T555
K
S
Q
E
R
E
E
T
E
S
K
C
D
S
E
Site 60
S557
Q
E
R
E
E
T
E
S
K
C
D
S
E
G
E
Site 61
S561
E
T
E
S
K
C
D
S
E
G
E
E
D
E
E
Site 62
T575
E
D
M
E
P
C
L
T
G
T
K
V
K
V
K
Site 63
T577
M
E
P
C
L
T
G
T
K
V
K
V
K
Y
G
Site 64
Y583
G
T
K
V
K
V
K
Y
G
R
G
K
T
Q
K
Site 65
T588
V
K
Y
G
R
G
K
T
Q
K
I
Y
E
A
S
Site 66
Y592
R
G
K
T
Q
K
I
Y
E
A
S
I
K
S
T
Site 67
Y612
E
V
L
Y
L
V
H
Y
Y
G
W
N
V
R
Y
Site 68
Y619
Y
Y
G
W
N
V
R
Y
D
E
W
V
K
A
D
Site 69
S651
K
A
K
N
K
E
D
S
E
K
D
E
K
R
D
Site 70
S664
R
D
E
E
R
Q
K
S
K
R
G
R
P
P
L
Site 71
S673
R
G
R
P
P
L
K
S
T
L
S
S
N
M
P
Site 72
T674
G
R
P
P
L
K
S
T
L
S
S
N
M
P
Y
Site 73
S676
P
P
L
K
S
T
L
S
S
N
M
P
Y
G
L
Site 74
S677
P
L
K
S
T
L
S
S
N
M
P
Y
G
L
S
Site 75
Y681
T
L
S
S
N
M
P
Y
G
L
S
K
T
A
N
Site 76
S684
S
N
M
P
Y
G
L
S
K
T
A
N
S
E
G
Site 77
T686
M
P
Y
G
L
S
K
T
A
N
S
E
G
K
S
Site 78
S689
G
L
S
K
T
A
N
S
E
G
K
S
D
S
C
Site 79
S693
T
A
N
S
E
G
K
S
D
S
C
S
S
D
S
Site 80
S695
N
S
E
G
K
S
D
S
C
S
S
D
S
E
T
Site 81
S697
E
G
K
S
D
S
C
S
S
D
S
E
T
E
D
Site 82
S698
G
K
S
D
S
C
S
S
D
S
E
T
E
D
A
Site 83
S700
S
D
S
C
S
S
D
S
E
T
E
D
A
L
E
Site 84
T702
S
C
S
S
D
S
E
T
E
D
A
L
E
K
N
Site 85
S716
N
L
I
N
E
E
L
S
L
K
D
E
L
E
K
Site 86
T750
I
L
K
E
N
D
R
T
Q
M
Q
P
L
E
T
Site 87
T779
F
G
N
K
M
E
K
T
E
E
V
K
K
E
A
Site 88
S789
V
K
K
E
A
E
K
S
P
K
G
K
G
R
R
Site 89
S797
P
K
G
K
G
R
R
S
K
T
K
D
L
S
L
Site 90
T799
G
K
G
R
R
S
K
T
K
D
L
S
L
E
I
Site 91
S803
R
S
K
T
K
D
L
S
L
E
I
I
K
I
S
Site 92
S811
L
E
I
I
K
I
S
S
F
G
Q
N
E
A
G
Site 93
S819
F
G
Q
N
E
A
G
S
E
P
H
I
E
A
H
Site 94
S827
E
P
H
I
E
A
H
S
L
E
L
S
S
L
D
Site 95
S831
E
A
H
S
L
E
L
S
S
L
D
N
K
N
F
Site 96
S832
A
H
S
L
E
L
S
S
L
D
N
K
N
F
S
Site 97
S839
S
L
D
N
K
N
F
S
S
A
T
E
D
E
I
Site 98
S840
L
D
N
K
N
F
S
S
A
T
E
D
E
I
D
Site 99
S863
K
R
K
I
L
G
Q
S
S
P
E
K
K
I
R
Site 100
S864
R
K
I
L
G
Q
S
S
P
E
K
K
I
R
I
Site 101
T880
N
G
M
E
M
T
N
T
V
S
Q
E
R
T
S
Site 102
S882
M
E
M
T
N
T
V
S
Q
E
R
T
S
D
C
Site 103
T886
N
T
V
S
Q
E
R
T
S
D
C
I
G
S
E
Site 104
S887
T
V
S
Q
E
R
T
S
D
C
I
G
S
E
G
Site 105
S913
R
E
N
E
G
M
P
S
L
I
A
E
S
N
Q
Site 106
S927
Q
C
I
Q
Q
L
T
S
E
R
F
D
S
P
A
Site 107
S932
L
T
S
E
R
F
D
S
P
A
E
E
T
V
N
Site 108
T973
D
L
D
E
K
D
K
T
S
I
E
D
V
A
V
Site 109
S983
E
D
V
A
V
E
S
S
E
S
N
S
L
V
S
Site 110
S987
V
E
S
S
E
S
N
S
L
V
S
I
P
P
A
Site 111
S990
S
E
S
N
S
L
V
S
I
P
P
A
L
P
P
Site 112
S1007
Q
H
N
F
S
V
A
S
P
L
T
L
S
Q
D
Site 113
T1010
F
S
V
A
S
P
L
T
L
S
Q
D
E
S
R
Site 114
S1012
V
A
S
P
L
T
L
S
Q
D
E
S
R
S
V
Site 115
S1016
L
T
L
S
Q
D
E
S
R
S
V
K
S
E
S
Site 116
S1018
L
S
Q
D
E
S
R
S
V
K
S
E
S
D
I
Site 117
S1021
D
E
S
R
S
V
K
S
E
S
D
I
T
I
E
Site 118
S1023
S
R
S
V
K
S
E
S
D
I
T
I
E
V
D
Site 119
T1026
V
K
S
E
S
D
I
T
I
E
V
D
S
I
A
Site 120
S1031
D
I
T
I
E
V
D
S
I
A
E
E
S
Q
E
Site 121
S1036
V
D
S
I
A
E
E
S
Q
E
G
L
C
E
R
Site 122
S1045
E
G
L
C
E
R
E
S
A
N
G
F
E
T
N
Site 123
T1051
E
S
A
N
G
F
E
T
N
V
A
S
G
T
C
Site 124
S1059
N
V
A
S
G
T
C
S
I
I
V
Q
E
R
E
Site 125
S1067
I
I
V
Q
E
R
E
S
R
E
K
G
Q
K
R
Site 126
S1076
E
K
G
Q
K
R
P
S
D
G
N
S
G
L
M
Site 127
S1080
K
R
P
S
D
G
N
S
G
L
M
A
K
K
Q
Site 128
T1090
M
A
K
K
Q
K
R
T
P
K
R
T
S
A
A
Site 129
S1095
K
R
T
P
K
R
T
S
A
A
A
K
N
E
K
Site 130
T1105
A
K
N
E
K
N
G
T
G
Q
S
S
D
S
E
Site 131
S1108
E
K
N
G
T
G
Q
S
S
D
S
E
D
L
P
Site 132
S1109
K
N
G
T
G
Q
S
S
D
S
E
D
L
P
V
Site 133
S1111
G
T
G
Q
S
S
D
S
E
D
L
P
V
L
D
Site 134
S1121
L
P
V
L
D
N
S
S
K
C
T
P
V
K
H
Site 135
T1124
L
D
N
S
S
K
C
T
P
V
K
H
L
N
V
Site 136
S1132
P
V
K
H
L
N
V
S
K
P
Q
K
L
A
R
Site 137
S1140
K
P
Q
K
L
A
R
S
P
A
R
I
S
P
H
Site 138
S1145
A
R
S
P
A
R
I
S
P
H
I
K
D
G
E
Site 139
S1163
H
R
E
K
H
P
N
S
S
P
R
T
Y
K
W
Site 140
S1164
R
E
K
H
P
N
S
S
P
R
T
Y
K
W
S
Site 141
T1167
H
P
N
S
S
P
R
T
Y
K
W
S
F
Q
L
Site 142
Y1168
P
N
S
S
P
R
T
Y
K
W
S
F
Q
L
N
Site 143
S1171
S
P
R
T
Y
K
W
S
F
Q
L
N
E
L
D
Site 144
S1182
N
E
L
D
N
M
N
S
T
E
R
I
S
F
L
Site 145
T1183
E
L
D
N
M
N
S
T
E
R
I
S
F
L
Q
Site 146
S1187
M
N
S
T
E
R
I
S
F
L
Q
E
K
L
Q
Site 147
Y1199
K
L
Q
E
I
R
K
Y
Y
M
S
L
K
S
E
Site 148
Y1200
L
Q
E
I
R
K
Y
Y
M
S
L
K
S
E
V
Site 149
S1202
E
I
R
K
Y
Y
M
S
L
K
S
E
V
A
T
Site 150
S1205
K
Y
Y
M
S
L
K
S
E
V
A
T
I
D
R
Site 151
T1209
S
L
K
S
E
V
A
T
I
D
R
R
R
K
R
Site 152
S1225
K
K
K
D
R
E
V
S
H
A
G
A
S
M
S
Site 153
S1230
E
V
S
H
A
G
A
S
M
S
S
A
S
S
D
Site 154
S1232
S
H
A
G
A
S
M
S
S
A
S
S
D
T
G
Site 155
S1233
H
A
G
A
S
M
S
S
A
S
S
D
T
G
M
Site 156
S1235
G
A
S
M
S
S
A
S
S
D
T
G
M
S
P
Site 157
S1236
A
S
M
S
S
A
S
S
D
T
G
M
S
P
S
Site 158
T1238
M
S
S
A
S
S
D
T
G
M
S
P
S
S
S
Site 159
S1241
A
S
S
D
T
G
M
S
P
S
S
S
S
P
P
Site 160
S1243
S
D
T
G
M
S
P
S
S
S
S
P
P
Q
N
Site 161
S1244
D
T
G
M
S
P
S
S
S
S
P
P
Q
N
V
Site 162
S1245
T
G
M
S
P
S
S
S
S
P
P
Q
N
V
L
Site 163
S1246
G
M
S
P
S
S
S
S
P
P
Q
N
V
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation