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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB3
Full Name:
Serpin B3
Alias:
SCC; SCCA; SCCA1; SCCA-1; SCCA-PD; SPB3; Squamous cell carcinoma antigen 1; T4-A
Type:
Protease inhibitor
Mass (Da):
44565
Number AA:
390
UniProt ID:
P29508
International Prot ID:
IPI00022204
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
S
L
S
E
A
N
T
K
F
M
F
D
L
F
Site 2
Y29
S
K
E
N
N
I
F
Y
S
P
I
S
I
T
S
Site 3
S30
K
E
N
N
I
F
Y
S
P
I
S
I
T
S
A
Site 4
T63
V
L
H
F
D
Q
V
T
E
N
T
T
G
K
A
Site 5
Y73
T
T
G
K
A
A
T
Y
H
V
D
R
S
G
N
Site 6
T90
H
Q
F
Q
K
L
L
T
E
F
N
K
S
T
D
Site 7
S95
L
L
T
E
F
N
K
S
T
D
A
Y
E
L
K
Site 8
Y99
F
N
K
S
T
D
A
Y
E
L
K
I
A
N
K
Site 9
T112
N
K
L
F
G
E
K
T
Y
L
F
L
Q
E
Y
Site 10
Y119
T
Y
L
F
L
Q
E
Y
L
D
A
I
K
K
F
Site 11
S130
I
K
K
F
Y
Q
T
S
V
E
S
V
D
F
A
Site 12
S149
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Site 13
S153
K
I
N
S
W
V
E
S
Q
T
N
E
K
I
K
Site 14
T155
N
S
W
V
E
S
Q
T
N
E
K
I
K
N
L
Site 15
T195
K
K
F
N
K
E
D
T
K
E
E
K
F
W
P
Site 16
Y216
S
I
Q
M
M
R
Q
Y
T
S
F
H
F
A
S
Site 17
S223
Y
T
S
F
H
F
A
S
L
E
D
V
Q
A
K
Site 18
T262
Q
K
L
E
E
K
L
T
A
E
K
L
M
E
W
Site 19
S271
E
K
L
M
E
W
T
S
L
Q
N
M
R
E
T
Site 20
T278
S
L
Q
N
M
R
E
T
R
V
D
L
H
L
P
Site 21
T298
E
S
Y
D
L
K
D
T
L
R
T
M
G
M
V
Site 22
S315
F
N
G
D
A
D
L
S
G
M
T
G
S
R
G
Site 23
S354
T
A
V
V
G
F
G
S
S
P
T
S
T
N
E
Site 24
S355
A
V
V
G
F
G
S
S
P
T
S
T
N
E
E
Site 25
S358
G
F
G
S
S
P
T
S
T
N
E
E
F
H
C
Site 26
T359
F
G
S
S
P
T
S
T
N
E
E
F
H
C
N
Site 27
Y384
K
T
N
S
I
L
F
Y
G
R
F
S
S
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation