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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OAS2
Full Name:
2'-5'-oligoadenylate synthase 2
Alias:
p69 OAS / p71 OAS
Type:
Mass (Da):
82431
Number AA:
719
UniProt ID:
P29728
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
N
G
E
S
Q
L
S
S
V
P
A
Site 2
S9
G
N
G
E
S
Q
L
S
S
V
P
A
Q
K
L
Site 3
S10
N
G
E
S
Q
L
S
S
V
P
A
Q
K
L
G
Site 4
Y23
L
G
W
F
I
Q
E
Y
L
K
P
Y
E
E
C
Site 5
T67
G
G
S
Y
G
R
K
T
V
L
R
G
N
S
D
Site 6
S93
Q
F
Q
D
Q
K
R
S
Q
R
D
I
L
D
K
Site 7
T101
Q
R
D
I
L
D
K
T
G
D
K
L
K
F
C
Site 8
S123
N
N
F
E
I
Q
K
S
L
D
G
F
T
I
Q
Site 9
T128
Q
K
S
L
D
G
F
T
I
Q
V
F
T
K
N
Site 10
S150
L
A
A
F
N
A
L
S
L
N
D
N
P
S
P
Site 11
S156
L
S
L
N
D
N
P
S
P
W
I
Y
R
E
L
Site 12
Y160
D
N
P
S
P
W
I
Y
R
E
L
K
R
S
L
Site 13
S166
I
Y
R
E
L
K
R
S
L
D
K
T
N
A
S
Site 14
T170
L
K
R
S
L
D
K
T
N
A
S
P
G
E
F
Site 15
S173
S
L
D
K
T
N
A
S
P
G
E
F
A
V
C
Site 16
S219
K
K
I
K
D
L
P
S
L
S
P
Y
A
L
E
Site 17
T298
I
L
D
P
V
D
P
T
N
N
V
S
G
D
K
Site 18
S321
E
A
Q
T
W
L
T
S
P
N
L
D
N
E
L
Site 19
S332
D
N
E
L
P
A
P
S
W
N
V
L
P
A
P
Site 20
T386
E
N
C
F
R
Q
S
T
A
K
I
Q
I
V
R
Site 21
S417
D
L
V
V
F
H
N
S
L
K
S
Y
T
S
Q
Site 22
S420
V
F
H
N
S
L
K
S
Y
T
S
Q
K
N
E
Site 23
Y421
F
H
N
S
L
K
S
Y
T
S
Q
K
N
E
R
Site 24
S423
N
S
L
K
S
Y
T
S
Q
K
N
E
R
H
K
Site 25
S453
K
E
E
E
L
E
V
S
F
E
P
P
K
W
K
Site 26
S466
W
K
A
P
R
V
L
S
F
S
L
K
S
K
V
Site 27
S477
K
S
K
V
L
N
E
S
V
S
F
D
V
L
P
Site 28
S493
F
N
A
L
G
Q
L
S
S
G
S
T
P
S
P
Site 29
S494
N
A
L
G
Q
L
S
S
G
S
T
P
S
P
E
Site 30
S496
L
G
Q
L
S
S
G
S
T
P
S
P
E
V
Y
Site 31
T497
G
Q
L
S
S
G
S
T
P
S
P
E
V
Y
A
Site 32
S499
L
S
S
G
S
T
P
S
P
E
V
Y
A
G
L
Site 33
Y510
Y
A
G
L
I
D
L
Y
K
S
S
D
L
P
G
Site 34
S512
G
L
I
D
L
Y
K
S
S
D
L
P
G
G
E
Site 35
S513
L
I
D
L
Y
K
S
S
D
L
P
G
G
E
F
Site 36
S534
L
Q
R
N
F
I
R
S
R
P
T
K
L
K
D
Site 37
T537
N
F
I
R
S
R
P
T
K
L
K
D
L
I
R
Site 38
Y550
I
R
L
V
K
H
W
Y
K
E
C
E
R
K
L
Site 39
S562
R
K
L
K
P
K
G
S
L
P
P
K
Y
A
L
Site 40
T588
S
G
V
P
D
F
D
T
A
E
G
F
R
T
V
Site 41
T594
D
T
A
E
G
F
R
T
V
L
E
L
V
T
Q
Site 42
T619
N
Y
N
F
E
D
E
T
V
R
K
F
L
L
S
Site 43
S626
T
V
R
K
F
L
L
S
Q
L
Q
K
T
R
P
Site 44
S666
E
A
K
E
W
L
S
S
P
C
F
K
D
G
T
Site 45
T673
S
P
C
F
K
D
G
T
G
N
P
I
P
P
W
Site 46
T687
W
K
V
P
T
M
Q
T
P
G
S
C
G
A
R
Site 47
S690
P
T
M
Q
T
P
G
S
C
G
A
R
I
H
P
Site 48
S704
P
I
V
N
E
M
F
S
S
R
S
H
R
I
L
Site 49
S705
I
V
N
E
M
F
S
S
R
S
H
R
I
L
N
Site 50
S707
N
E
M
F
S
S
R
S
H
R
I
L
N
N
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation