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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNA11
Full Name:
Guanine nucleotide-binding protein subunit alpha-11
Alias:
Alpha-11; GA11; Guanine nucleotide-binding protein G(y) subunit alpha
Type:
G protein, trimeric, alpha subunit
Mass (Da):
42123
Number AA:
359
UniProt ID:
P29992
International Prot ID:
IPI00305551
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0006471
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
M
M
A
C
C
L
S
D
E
V
K
E
S
K
Site 2
S18
L
S
D
E
V
K
E
S
K
R
I
N
A
E
I
Site 3
S50
L
L
L
G
T
G
E
S
G
K
S
T
F
I
K
Site 4
S53
G
T
G
E
S
G
K
S
T
F
I
K
Q
M
R
Site 5
T54
T
G
E
S
G
K
S
T
F
I
K
Q
M
R
I
Site 6
Y67
R
I
I
H
G
A
G
Y
S
E
E
D
K
R
G
Site 7
S68
I
I
H
G
A
G
Y
S
E
E
D
K
R
G
F
Site 8
T76
E
E
D
K
R
G
F
T
K
L
V
Y
Q
N
I
Site 9
Y80
R
G
F
T
K
L
V
Y
Q
N
I
F
T
A
M
Site 10
Y103
T
L
K
I
L
Y
K
Y
E
Q
N
K
A
N
A
Site 11
T123
V
D
V
E
K
V
T
T
F
E
H
Q
Y
V
S
Site 12
T134
Q
Y
V
S
A
I
K
T
L
W
E
D
P
G
I
Site 13
Y145
D
P
G
I
Q
E
C
Y
D
R
R
R
E
Y
Q
Site 14
Y151
C
Y
D
R
R
R
E
Y
Q
L
S
D
S
A
K
Site 15
S154
R
R
R
E
Y
Q
L
S
D
S
A
K
Y
Y
L
Site 16
S156
R
E
Y
Q
L
S
D
S
A
K
Y
Y
L
T
D
Site 17
Y159
Q
L
S
D
S
A
K
Y
Y
L
T
D
V
D
R
Site 18
Y160
L
S
D
S
A
K
Y
Y
L
T
D
V
D
R
I
Site 19
T162
D
S
A
K
Y
Y
L
T
D
V
D
R
I
A
T
Site 20
T169
T
D
V
D
R
I
A
T
L
G
Y
L
P
T
Q
Site 21
Y172
D
R
I
A
T
L
G
Y
L
P
T
Q
Q
D
V
Site 22
Y192
P
T
T
G
I
I
E
Y
P
F
D
L
E
N
I
Site 23
S211
V
D
V
G
G
Q
R
S
E
R
R
K
W
I
H
Site 24
T257
E
S
K
A
L
F
R
T
I
I
T
Y
P
W
F
Site 25
Y261
L
F
R
T
I
I
T
Y
P
W
F
Q
N
S
S
Site 26
Y291
L
Y
S
H
L
V
D
Y
F
P
E
F
D
G
P
Site 27
S320
F
V
D
L
N
P
D
S
D
K
I
I
Y
S
H
Site 28
Y356
L
Q
L
N
L
K
E
Y
N
L
V
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation