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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP2R1B
Full Name:
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Alias:
PP2A, subunit A, PR65-beta isoform
Type:
Mass (Da):
66196
Number AA:
601
UniProt ID:
P30154
International Prot ID:
IPI00294178
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003823
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S43
D
V
Q
L
R
L
N
S
I
K
K
L
S
T
I
Site 2
T68
S
E
L
L
P
F
L
T
D
T
I
Y
D
E
D
Site 3
T110
P
P
L
E
N
L
A
T
V
E
E
T
V
V
R
Site 4
S123
V
R
D
K
A
V
E
S
L
R
Q
I
S
Q
E
Site 5
S128
V
E
S
L
R
Q
I
S
Q
E
H
T
P
V
A
Site 6
T132
R
Q
I
S
Q
E
H
T
P
V
A
L
E
A
Y
Site 7
S149
P
L
V
K
R
L
A
S
G
D
W
F
T
S
R
Site 8
T154
L
A
S
G
D
W
F
T
S
R
T
S
A
C
G
Site 9
S155
A
S
G
D
W
F
T
S
R
T
S
A
C
G
L
Site 10
S171
S
V
C
Y
P
R
A
S
N
A
V
K
A
E
I
Site 11
S184
E
I
R
Q
Q
F
R
S
L
C
S
D
D
T
P
Site 12
T190
R
S
L
C
S
D
D
T
P
M
V
R
R
A
A
Site 13
S199
M
V
R
R
A
A
A
S
K
L
G
E
F
A
K
Site 14
S212
A
K
V
L
E
L
D
S
V
K
S
E
I
V
P
Site 15
S223
E
I
V
P
L
F
T
S
L
A
S
D
E
Q
D
Site 16
S231
L
A
S
D
E
Q
D
S
V
R
L
L
A
V
E
Site 17
T254
L
S
Q
D
D
L
E
T
L
V
M
P
T
L
R
Site 18
Y273
D
K
S
W
R
V
R
Y
M
V
A
D
R
F
S
Site 19
S280
Y
M
V
A
D
R
F
S
E
L
Q
K
A
M
G
Site 20
Y341
I
M
N
Q
I
L
P
Y
I
K
E
L
V
S
D
Site 21
S398
D
V
R
L
N
I
I
S
N
L
D
C
V
N
E
Site 22
T493
G
T
E
W
A
Q
N
T
I
V
P
K
V
L
V
Site 23
Y507
V
M
A
N
D
P
N
Y
L
H
R
M
T
T
L
Site 24
Y589
D
E
D
M
D
V
K
Y
F
A
Q
E
A
I
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation