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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CD6
Full Name:
T-cell differentiation antigen CD6
Alias:
T12;TP120
Type:
Receptor
Mass (Da):
71829
Number AA:
668
UniProt ID:
P30203
International Prot ID:
IPI00025700
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005044
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y327
H
S
L
S
G
R
M
Y
Y
S
C
N
G
E
E
Site 2
S341
E
L
T
L
S
N
C
S
W
R
F
N
N
S
N
Site 3
S405
E
L
M
L
L
I
P
S
I
V
L
G
I
L
L
Site 4
T443
V
N
H
Q
H
L
P
T
T
I
P
A
G
S
N
Site 5
T444
N
H
Q
H
L
P
T
T
I
P
A
G
S
N
S
Site 6
S449
P
T
T
I
P
A
G
S
N
S
Y
Q
P
V
P
Site 7
S451
T
I
P
A
G
S
N
S
Y
Q
P
V
P
I
T
Site 8
S478
Q
A
P
P
P
E
D
S
D
S
G
S
D
S
D
Site 9
S480
P
P
P
E
D
S
D
S
G
S
D
S
D
Y
E
Site 10
S482
P
E
D
S
D
S
G
S
D
S
D
Y
E
H
Y
Site 11
S484
D
S
D
S
G
S
D
S
D
Y
E
H
Y
D
F
Site 12
Y486
D
S
G
S
D
S
D
Y
E
H
Y
D
F
S
A
Site 13
Y489
S
D
S
D
Y
E
H
Y
D
F
S
A
Q
P
P
Site 14
S492
D
Y
E
H
Y
D
F
S
A
Q
P
P
V
A
L
Site 15
T501
Q
P
P
V
A
L
T
T
F
Y
N
S
Q
R
H
Site 16
Y503
P
V
A
L
T
T
F
Y
N
S
Q
R
H
R
V
Site 17
S505
A
L
T
T
F
Y
N
S
Q
R
H
R
V
T
D
Site 18
T511
N
S
Q
R
H
R
V
T
D
E
E
V
Q
Q
S
Site 19
S518
T
D
E
E
V
Q
Q
S
R
F
Q
M
P
P
L
Site 20
S535
G
L
E
E
L
H
A
S
H
I
P
T
A
N
P
Site 21
T539
L
H
A
S
H
I
P
T
A
N
P
G
H
C
I
Site 22
T547
A
N
P
G
H
C
I
T
D
P
P
S
L
G
P
Site 23
S551
H
C
I
T
D
P
P
S
L
G
P
Q
Y
H
P
Site 24
Y556
P
P
S
L
G
P
Q
Y
H
P
R
S
N
S
E
Site 25
S560
G
P
Q
Y
H
P
R
S
N
S
E
S
S
T
S
Site 26
S562
Q
Y
H
P
R
S
N
S
E
S
S
T
S
S
G
Site 27
S564
H
P
R
S
N
S
E
S
S
T
S
S
G
E
D
Site 28
S565
P
R
S
N
S
E
S
S
T
S
S
G
E
D
Y
Site 29
T566
R
S
N
S
E
S
S
T
S
S
G
E
D
Y
C
Site 30
S567
S
N
S
E
S
S
T
S
S
G
E
D
Y
C
N
Site 31
S568
N
S
E
S
S
T
S
S
G
E
D
Y
C
N
S
Site 32
Y572
S
T
S
S
G
E
D
Y
C
N
S
P
K
S
K
Site 33
S575
S
G
E
D
Y
C
N
S
P
K
S
K
L
P
P
Site 34
S589
P
W
N
P
Q
V
F
S
S
E
R
S
S
F
L
Site 35
S590
W
N
P
Q
V
F
S
S
E
R
S
S
F
L
E
Site 36
S593
Q
V
F
S
S
E
R
S
S
F
L
E
Q
P
P
Site 37
S594
V
F
S
S
E
R
S
S
F
L
E
Q
P
P
N
Site 38
T607
P
N
L
E
L
A
G
T
Q
P
A
F
S
A
G
Site 39
S612
A
G
T
Q
P
A
F
S
A
G
P
P
A
D
D
Site 40
S620
A
G
P
P
A
D
D
S
S
S
T
S
S
G
E
Site 41
S621
G
P
P
A
D
D
S
S
S
T
S
S
G
E
W
Site 42
S622
P
P
A
D
D
S
S
S
T
S
S
G
E
W
Y
Site 43
S624
A
D
D
S
S
S
T
S
S
G
E
W
Y
Q
N
Site 44
S625
D
D
S
S
S
T
S
S
G
E
W
Y
Q
N
F
Site 45
Y629
S
T
S
S
G
E
W
Y
Q
N
F
Q
P
P
P
Site 46
S640
Q
P
P
P
Q
P
P
S
E
E
Q
F
G
C
P
Site 47
S649
E
Q
F
G
C
P
G
S
P
S
P
Q
P
D
S
Site 48
S651
F
G
C
P
G
S
P
S
P
Q
P
D
S
T
D
Site 49
S656
S
P
S
P
Q
P
D
S
T
D
N
D
D
Y
D
Site 50
T657
P
S
P
Q
P
D
S
T
D
N
D
D
Y
D
D
Site 51
Y662
D
S
T
D
N
D
D
Y
D
D
I
S
A
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation