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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHRNA5
Full Name:
Neuronal acetylcholine receptor subunit alpha-5
Alias:
Type:
Mass (Da):
53054
Number AA:
468
UniProt ID:
P30532
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
R
G
S
G
P
R
A
L
R
L
Site 2
S38
G
G
A
Q
R
G
L
S
E
P
S
S
I
A
K
Site 3
S42
R
G
L
S
E
P
S
S
I
A
K
H
E
D
S
Site 4
S49
S
I
A
K
H
E
D
S
L
L
K
D
L
F
Q
Site 5
Y58
L
K
D
L
F
Q
D
Y
E
R
W
V
R
P
V
Site 6
Y115
L
R
W
N
P
D
D
Y
G
G
I
K
V
I
R
Site 7
S125
I
K
V
I
R
V
P
S
D
S
V
W
T
P
D
Site 8
S147
D
G
R
F
E
G
T
S
T
K
T
V
I
R
Y
Site 9
T148
G
R
F
E
G
T
S
T
K
T
V
I
R
Y
N
Site 10
T150
F
E
G
T
S
T
K
T
V
I
R
Y
N
G
T
Site 11
T157
T
V
I
R
Y
N
G
T
V
T
W
T
P
P
A
Site 12
T159
I
R
Y
N
G
T
V
T
W
T
P
P
A
N
Y
Site 13
T161
Y
N
G
T
V
T
W
T
P
P
A
N
Y
K
S
Site 14
S168
T
P
P
A
N
Y
K
S
S
C
T
I
D
V
T
Site 15
S169
P
P
A
N
Y
K
S
S
C
T
I
D
V
T
F
Site 16
T192
S
M
K
F
G
S
W
T
Y
D
G
S
Q
V
D
Site 17
S196
G
S
W
T
Y
D
G
S
Q
V
D
I
I
L
E
Site 18
S222
N
G
E
W
E
I
V
S
A
T
G
S
K
G
N
Site 19
S226
E
I
V
S
A
T
G
S
K
G
N
R
T
D
S
Site 20
S343
N
I
H
H
R
S
S
S
T
H
N
A
M
A
P
Site 21
Y373
M
R
S
H
V
D
R
Y
F
T
Q
K
E
E
T
Site 22
T375
S
H
V
D
R
Y
F
T
Q
K
E
E
T
E
S
Site 23
T380
Y
F
T
Q
K
E
E
T
E
S
G
S
G
P
K
Site 24
S382
T
Q
K
E
E
T
E
S
G
S
G
P
K
S
S
Site 25
S384
K
E
E
T
E
S
G
S
G
P
K
S
S
R
N
Site 26
S388
E
S
G
S
G
P
K
S
S
R
N
T
L
E
A
Site 27
S389
S
G
S
G
P
K
S
S
R
N
T
L
E
A
A
Site 28
T392
G
P
K
S
S
R
N
T
L
E
A
A
L
D
S
Site 29
S399
T
L
E
A
A
L
D
S
I
R
Y
I
T
R
H
Site 30
Y402
A
A
L
D
S
I
R
Y
I
T
R
H
I
M
K
Site 31
T404
L
D
S
I
R
Y
I
T
R
H
I
M
K
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation