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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNA15
Full Name:
Guanine nucleotide-binding protein subunit alpha-15
Alias:
G alpha-15; G alpha-16; Galpha15; GNA16; guanine nucleotide binding protein (G protein) alpha 15 (Gq class); guanine nucleotide-binding protein alpha-15
Type:
G protein, heterotrimeric
Mass (Da):
43508
Number AA:
374
UniProt ID:
P30679
International Prot ID:
IPI00027243
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005834
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007207
GO:0007204
GO:0006471
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S53
L
L
L
G
P
G
E
S
G
K
S
T
F
I
K
Site 2
S56
G
P
G
E
S
G
K
S
T
F
I
K
Q
M
R
Site 3
T57
P
G
E
S
G
K
S
T
F
I
K
Q
M
R
I
Site 4
S71
I
I
H
G
A
G
Y
S
E
E
E
R
K
G
F
Site 5
Y83
K
G
F
R
P
L
V
Y
Q
N
I
F
V
S
M
Site 6
S105
E
R
L
Q
I
P
F
S
R
P
E
S
K
H
H
Site 7
S109
I
P
F
S
R
P
E
S
K
H
H
A
S
L
V
Site 8
S114
P
E
S
K
H
H
A
S
L
V
M
S
Q
D
P
Site 9
S118
H
H
A
S
L
V
M
S
Q
D
P
Y
K
V
T
Site 10
Y122
L
V
M
S
Q
D
P
Y
K
V
T
T
F
E
K
Site 11
T126
Q
D
P
Y
K
V
T
T
F
E
K
R
Y
A
A
Site 12
Y148
D
A
G
I
R
A
C
Y
E
R
R
R
E
F
H
Site 13
S159
R
E
F
H
L
L
D
S
A
V
Y
Y
L
S
H
Site 14
T171
L
S
H
L
E
R
I
T
E
E
G
Y
V
P
T
Site 15
Y175
E
R
I
T
E
E
G
Y
V
P
T
A
Q
D
V
Site 16
T189
V
L
R
S
R
M
P
T
T
G
I
N
E
Y
C
Site 17
T190
L
R
S
R
M
P
T
T
G
I
N
E
Y
C
F
Site 18
S214
V
D
V
G
G
Q
K
S
E
R
K
K
W
I
H
Site 19
Y238
Y
L
A
S
L
S
E
Y
D
Q
C
L
E
E
N
Site 20
S254
Q
E
N
R
M
K
E
S
L
A
L
F
G
T
I
Site 21
S271
L
P
W
F
K
S
T
S
V
I
L
F
L
N
K
Site 22
S289
L
E
E
K
I
P
T
S
H
L
A
T
Y
F
P
Site 23
T293
I
P
T
S
H
L
A
T
Y
F
P
S
F
Q
G
Site 24
Y294
P
T
S
H
L
A
T
Y
F
P
S
F
Q
G
P
Site 25
S297
H
L
A
T
Y
F
P
S
F
Q
G
P
K
Q
D
Site 26
Y316
K
R
F
I
L
D
M
Y
T
R
M
Y
T
G
C
Site 27
Y320
L
D
M
Y
T
R
M
Y
T
G
C
V
D
G
P
Site 28
T321
D
M
Y
T
R
M
Y
T
G
C
V
D
G
P
E
Site 29
S336
G
S
K
K
G
A
R
S
R
R
L
F
S
H
Y
Site 30
S341
A
R
S
R
R
L
F
S
H
Y
T
C
A
T
D
Site 31
Y343
S
R
R
L
F
S
H
Y
T
C
A
T
D
T
Q
Site 32
S362
V
F
K
D
V
R
D
S
V
L
A
R
Y
L
D
Site 33
Y367
R
D
S
V
L
A
R
Y
L
D
E
I
N
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation