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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC7A1
Full Name:
High affinity cationic amino acid transporter 1
Alias:
Ecotropic retroviral leukemia receptor homolog;Ecotropic retrovirus receptor homolog;Solute carrier family 7 member 1;System Y+ basic amino acid transporter
Type:
Mass (Da):
67638
Number AA:
629
UniProt ID:
P30825
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
R
R
K
V
V
D
C
S
R
E
E
T
R
L
S
Site 2
T26
V
D
C
S
R
E
E
T
R
L
S
R
C
L
N
Site 3
S29
S
R
E
E
T
R
L
S
R
C
L
N
T
F
D
Site 4
T94
F
G
A
R
V
P
K
T
G
S
A
Y
L
Y
S
Site 5
S96
A
R
V
P
K
T
G
S
A
Y
L
Y
S
Y
V
Site 6
Y98
V
P
K
T
G
S
A
Y
L
Y
S
Y
V
T
V
Site 7
Y100
K
T
G
S
A
Y
L
Y
S
Y
V
T
V
G
E
Site 8
Y102
G
S
A
Y
L
Y
S
Y
V
T
V
G
E
L
W
Site 9
T150
P
I
G
E
F
S
R
T
H
M
T
L
N
A
P
Site 10
T220
S
V
K
N
W
Q
L
T
E
E
D
F
G
N
T
Site 11
S228
E
E
D
F
G
N
T
S
G
R
L
C
L
N
N
Site 12
T237
R
L
C
L
N
N
D
T
K
E
G
K
P
G
V
Site 13
S321
Y
F
C
L
D
N
N
S
P
L
P
D
A
F
K
Site 14
T382
L
A
N
V
N
D
R
T
K
T
P
I
I
A
T
Site 15
T384
N
V
N
D
R
T
K
T
P
I
I
A
T
L
A
Site 16
Y441
P
E
Q
P
N
L
V
Y
Q
M
A
S
T
S
D
Site 17
S447
V
Y
Q
M
A
S
T
S
D
E
L
D
P
A
D
Site 18
S460
A
D
Q
N
E
L
A
S
T
N
D
S
Q
L
G
Site 19
T461
D
Q
N
E
L
A
S
T
N
D
S
Q
L
G
F
Site 20
S464
E
L
A
S
T
N
D
S
Q
L
G
F
L
P
E
Site 21
S482
F
S
L
K
T
I
L
S
P
K
N
M
E
P
S
Site 22
S489
S
P
K
N
M
E
P
S
K
I
S
G
L
I
V
Site 23
S552
V
I
W
R
Q
P
E
S
K
T
K
L
S
F
K
Site 24
S557
P
E
S
K
T
K
L
S
F
K
V
P
F
L
P
Site 25
S608
F
G
Y
G
L
W
H
S
E
E
A
S
L
D
A
Site 26
S612
L
W
H
S
E
E
A
S
L
D
A
D
Q
A
R
Site 27
T620
L
D
A
D
Q
A
R
T
P
D
G
N
L
D
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation