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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALDH1B1
Full Name:
Aldehyde dehydrogenase X, mitochondrial
Alias:
Acetaldehyde dehydrogenase 5; AL1B1; Aldehyde dehydrogenase 1 family, member B1; Aldehyde dehydrogenase X, mitochondrial; ALDH class 2; ALDH5; ALDHX; EC 1.2.1.3
Type:
Amino Acid Metabolism - lysine degradation; Oxidoreductase; Amino Acid Metabolism - arginine and proline; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - ascorbate and aldarate; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - pyruvate; Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - tryptophan; EC 1.2.1.3; Carbohydrate Metabolism - glycolysis and gluconeogenesis
Mass (Da):
57238
Number AA:
517
UniProt ID:
P30837
International Prot ID:
IPI00103467
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0004029
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
F
L
A
P
R
L
L
S
L
Q
G
R
T
A
R
Site 2
T16
L
L
S
L
Q
G
R
T
A
R
Y
S
S
A
A
Site 3
S20
Q
G
R
T
A
R
Y
S
S
A
A
A
L
P
S
Site 4
S21
G
R
T
A
R
Y
S
S
A
A
A
L
P
S
P
Site 5
Y36
I
L
N
P
D
I
P
Y
N
Q
L
F
I
N
N
Site 6
T53
Q
D
A
V
S
K
K
T
F
P
T
V
N
P
T
Site 7
T56
V
S
K
K
T
F
P
T
V
N
P
T
T
G
E
Site 8
S91
R
E
A
F
R
L
G
S
P
W
R
R
M
D
A
Site 9
S99
P
W
R
R
M
D
A
S
E
R
G
R
L
L
N
Site 10
S121
R
D
R
V
Y
L
A
S
L
E
T
L
D
N
G
Site 11
Y135
G
K
P
F
Q
E
S
Y
A
L
D
L
D
E
V
Site 12
Y148
E
V
I
K
V
Y
R
Y
F
A
G
W
A
D
K
Site 13
T283
D
S
N
L
K
R
V
T
L
E
L
G
G
K
S
Site 14
S292
E
L
G
G
K
S
P
S
I
V
L
A
D
A
D
Site 15
Y332
T
F
V
E
E
S
I
Y
N
E
F
L
E
R
T
Site 16
T339
Y
N
E
F
L
E
R
T
V
E
K
A
K
Q
R
Site 17
T356
G
N
P
F
E
L
D
T
Q
Q
G
P
Q
V
D
Site 18
Y373
Q
F
E
R
V
L
G
Y
I
Q
L
G
Q
K
E
Site 19
T401
R
G
F
F
I
K
P
T
V
F
G
G
V
Q
D
Site 20
Y458
R
D
L
D
K
A
M
Y
F
T
Q
A
L
Q
A
Site 21
T480
Y
N
I
V
T
C
H
T
P
F
G
G
F
K
E
Site 22
S488
P
F
G
G
F
K
E
S
G
N
G
R
E
L
G
Site 23
Y502
G
E
D
G
L
K
A
Y
T
E
V
K
T
V
T
Site 24
T507
K
A
Y
T
E
V
K
T
V
T
I
K
V
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation