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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GDI1
Full Name:
Rab GDP dissociation inhibitor alpha
Alias:
FLJ41411; GDI-1; GDIA; GDIL; GDP dissociation inhibitor 1; Guanosine diphosphate dissociation inhibitor 1; Mental retardation, X-linked 41; Mental retardation, X-linked 48; MRX41; MRX48; Oligophrenin 2; Oligophrenin-2; OPHN2; Protein XAP-4; Rab GDI alpha; Rab GDP-dissociation inhibitor, alpha; RABGDIA; XAP4; XAP-4
Type:
G protein regulator, misc.
Mass (Da):
50583
Number AA:
447
UniProt ID:
P31150
International Prot ID:
IPI00010154
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005093
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0043087
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
L
H
M
D
R
N
P
Y
Y
G
G
E
S
S
S
Site 2
Y39
H
M
D
R
N
P
Y
Y
G
G
E
S
S
S
I
Site 3
S43
N
P
Y
Y
G
G
E
S
S
S
I
T
P
L
E
Site 4
S44
P
Y
Y
G
G
E
S
S
S
I
T
P
L
E
E
Site 5
S45
Y
Y
G
G
E
S
S
S
I
T
P
L
E
E
L
Site 6
T47
G
G
E
S
S
S
I
T
P
L
E
E
L
Y
K
Site 7
Y53
I
T
P
L
E
E
L
Y
K
R
F
Q
L
L
E
Site 8
S65
L
L
E
G
P
P
E
S
M
G
R
G
R
D
W
Site 9
Y93
Q
L
V
K
M
L
L
Y
T
E
V
T
R
Y
L
Site 10
T94
L
V
K
M
L
L
Y
T
E
V
T
R
Y
L
D
Site 11
Y99
L
Y
T
E
V
T
R
Y
L
D
F
K
V
V
E
Site 12
S108
D
F
K
V
V
E
G
S
F
V
Y
K
G
G
K
Site 13
Y111
V
V
E
G
S
F
V
Y
K
G
G
K
I
Y
K
Site 14
Y117
V
Y
K
G
G
K
I
Y
K
V
P
S
T
E
T
Site 15
S121
G
K
I
Y
K
V
P
S
T
E
T
E
A
L
A
Site 16
T122
K
I
Y
K
V
P
S
T
E
T
E
A
L
A
S
Site 17
T157
F
D
E
N
D
P
K
T
F
E
G
V
D
P
Q
Site 18
T165
F
E
G
V
D
P
Q
T
T
S
M
R
D
V
Y
Site 19
S167
G
V
D
P
Q
T
T
S
M
R
D
V
Y
R
K
Site 20
Y172
T
T
S
M
R
D
V
Y
R
K
F
D
L
G
Q
Site 21
Y192
T
G
H
A
L
A
L
Y
R
T
D
D
Y
L
D
Site 22
Y197
A
L
Y
R
T
D
D
Y
L
D
Q
P
C
L
E
Site 23
T205
L
D
Q
P
C
L
E
T
V
N
R
I
K
L
Y
Site 24
S213
V
N
R
I
K
L
Y
S
E
S
L
A
R
Y
G
Site 25
S215
R
I
K
L
Y
S
E
S
L
A
R
Y
G
K
S
Site 26
Y219
Y
S
E
S
L
A
R
Y
G
K
S
P
Y
L
Y
Site 27
S222
S
L
A
R
Y
G
K
S
P
Y
L
Y
P
L
Y
Site 28
Y224
A
R
Y
G
K
S
P
Y
L
Y
P
L
Y
G
L
Site 29
Y226
Y
G
K
S
P
Y
L
Y
P
L
Y
G
L
G
E
Site 30
Y229
S
P
Y
L
Y
P
L
Y
G
L
G
E
L
P
Q
Site 31
S242
P
Q
G
F
A
R
L
S
A
I
Y
G
G
T
Y
Site 32
Y249
S
A
I
Y
G
G
T
Y
M
L
N
K
P
V
D
Site 33
S270
G
K
V
V
G
V
K
S
E
G
E
V
A
R
C
Site 34
S285
K
Q
L
I
C
D
P
S
Y
I
P
D
R
V
R
Site 35
Y286
Q
L
I
C
D
P
S
Y
I
P
D
R
V
R
K
Site 36
Y333
V
N
R
K
S
D
I
Y
V
C
M
I
S
Y
A
Site 37
Y339
I
Y
V
C
M
I
S
Y
A
H
N
V
A
A
Q
Site 38
Y349
N
V
A
A
Q
G
K
Y
I
A
I
A
S
T
T
Site 39
S354
G
K
Y
I
A
I
A
S
T
T
V
E
T
T
D
Site 40
S384
D
Q
K
F
V
A
I
S
D
L
Y
E
P
I
D
Site 41
Y421
C
N
D
I
K
D
I
Y
K
R
M
A
G
T
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation