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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXC8
Full Name:
Homeobox protein Hox-C8
Alias:
Homeo box 3A; Homeo box C8; Homeobox C8; HOX3; Hox-3.1, mouse, homolog of; HOX3A; Hox-3A; HXC8
Type:
Transcription factor
Mass (Da):
27755
Number AA:
242
UniProt ID:
P31273
International Prot ID:
IPI00010756
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
V
N
P
L
F
S
K
Y
K
A
G
E
S
L
E
Site 2
S18
S
K
Y
K
A
G
E
S
L
E
P
A
Y
Y
D
Site 3
Y23
G
E
S
L
E
P
A
Y
Y
D
C
R
F
P
Q
Site 4
Y24
E
S
L
E
P
A
Y
Y
D
C
R
F
P
Q
S
Site 5
S31
Y
D
C
R
F
P
Q
S
V
G
R
S
H
A
L
Site 6
S35
F
P
Q
S
V
G
R
S
H
A
L
V
Y
G
P
Site 7
Y40
G
R
S
H
A
L
V
Y
G
P
G
G
S
A
P
Site 8
S45
L
V
Y
G
P
G
G
S
A
P
G
F
Q
H
A
Site 9
T64
Q
D
F
F
H
H
G
T
S
G
I
S
N
S
G
Site 10
S65
D
F
F
H
H
G
T
S
G
I
S
N
S
G
Y
Site 11
S70
G
T
S
G
I
S
N
S
G
Y
Q
Q
N
P
C
Site 12
Y72
S
G
I
S
N
S
G
Y
Q
Q
N
P
C
S
L
Site 13
S80
Q
Q
N
P
C
S
L
S
C
H
G
D
A
S
K
Site 14
Y89
H
G
D
A
S
K
F
Y
G
Y
E
A
L
P
R
Site 15
S98
Y
E
A
L
P
R
Q
S
L
Y
G
A
Q
Q
E
Site 16
Y100
A
L
P
R
Q
S
L
Y
G
A
Q
Q
E
A
S
Site 17
S107
Y
G
A
Q
Q
E
A
S
V
V
Q
Y
P
D
C
Site 18
Y111
Q
E
A
S
V
V
Q
Y
P
D
C
K
S
S
A
Site 19
S116
V
Q
Y
P
D
C
K
S
S
A
N
T
N
S
S
Site 20
T120
D
C
K
S
S
A
N
T
N
S
S
E
G
Q
G
Site 21
S122
K
S
S
A
N
T
N
S
S
E
G
Q
G
H
L
Site 22
S123
S
S
A
N
T
N
S
S
E
G
Q
G
H
L
N
Site 23
S133
Q
G
H
L
N
Q
N
S
S
P
S
L
M
F
P
Site 24
S134
G
H
L
N
Q
N
S
S
P
S
L
M
F
P
W
Site 25
S136
L
N
Q
N
S
S
P
S
L
M
F
P
W
M
R
Site 26
S151
P
H
A
P
G
R
R
S
G
R
Q
T
Y
S
R
Site 27
T155
G
R
R
S
G
R
Q
T
Y
S
R
Y
Q
T
L
Site 28
Y156
R
R
S
G
R
Q
T
Y
S
R
Y
Q
T
L
E
Site 29
S157
R
S
G
R
Q
T
Y
S
R
Y
Q
T
L
E
L
Site 30
Y159
G
R
Q
T
Y
S
R
Y
Q
T
L
E
L
E
K
Site 31
T161
Q
T
Y
S
R
Y
Q
T
L
E
L
E
K
E
F
Site 32
Y173
K
E
F
L
F
N
P
Y
L
T
R
K
R
R
I
Site 33
S183
R
K
R
R
I
E
V
S
H
A
L
G
L
T
E
Site 34
T189
V
S
H
A
L
G
L
T
E
R
Q
V
K
I
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation