KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FMO3
Full Name:
Dimethylaniline monooxygenase [N-oxide-forming] 3
Alias:
Dimethylaniline oxidase 3;FMO II;FMO form 2;Hepatic flavin-containing monooxygenase 3
Type:
Mass (Da):
60033
Number AA:
532
UniProt ID:
P31513
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
S
G
L
A
S
I
R
S
C
L
E
E
G
L
E
Site 2
S44
I
G
G
L
W
K
F
S
D
H
A
E
E
G
R
Site 3
S53
H
A
E
E
G
R
A
S
I
Y
K
S
V
F
S
Site 4
Y55
E
E
G
R
A
S
I
Y
K
S
V
F
S
N
S
Site 5
S57
G
R
A
S
I
Y
K
S
V
F
S
N
S
S
K
Site 6
S60
S
I
Y
K
S
V
F
S
N
S
S
K
E
M
M
Site 7
S63
K
S
V
F
S
N
S
S
K
E
M
M
C
F
P
Site 8
Y90
H
N
S
K
I
Q
E
Y
I
I
A
F
A
K
E
Site 9
Y103
K
E
K
N
L
L
K
Y
I
Q
F
K
T
F
V
Site 10
T108
L
K
Y
I
Q
F
K
T
F
V
S
S
V
N
K
Site 11
S112
Q
F
K
T
F
V
S
S
V
N
K
H
P
D
F
Site 12
T128
T
T
G
Q
W
D
V
T
T
E
R
D
G
K
K
Site 13
T129
T
G
Q
W
D
V
T
T
E
R
D
G
K
K
E
Site 14
Y152
V
C
S
G
H
H
V
Y
P
N
L
P
K
E
S
Site 15
S159
Y
P
N
L
P
K
E
S
F
P
G
L
N
H
F
Site 16
S173
F
K
G
K
C
F
H
S
R
D
Y
K
E
P
G
Site 17
Y176
K
C
F
H
S
R
D
Y
K
E
P
G
V
F
N
Site 18
S213
T
A
E
Q
V
M
I
S
S
R
S
G
S
W
V
Site 19
S214
A
E
Q
V
M
I
S
S
R
S
G
S
W
V
M
Site 20
S216
Q
V
M
I
S
S
R
S
G
S
W
V
M
S
R
Site 21
S218
M
I
S
S
R
S
G
S
W
V
M
S
R
V
W
Site 22
Y229
S
R
V
W
D
N
G
Y
P
W
D
M
L
L
V
Site 23
Y256
T
A
I
S
D
W
L
Y
V
K
Q
M
N
A
R
Site 24
T309
N
V
K
E
F
T
E
T
S
A
I
F
E
D
G
Site 25
S341
A
Y
P
F
L
D
E
S
I
I
K
S
R
N
N
Site 26
S345
L
D
E
S
I
I
K
S
R
N
N
E
I
I
L
Site 27
T398
Q
V
I
K
G
T
C
T
L
P
S
M
E
D
M
Site 28
T428
G
K
S
E
T
I
Q
T
D
Y
I
V
Y
M
D
Site 29
Y430
S
E
T
I
Q
T
D
Y
I
V
Y
M
D
E
L
Site 30
S439
V
Y
M
D
E
L
S
S
F
I
G
A
K
P
N
Site 31
Y462
P
K
L
A
M
E
V
Y
F
G
P
C
S
P
Y
Site 32
Y469
Y
F
G
P
C
S
P
Y
Q
F
R
L
V
G
P
Site 33
T488
G
A
R
N
A
I
L
T
Q
W
D
R
S
L
K
Site 34
S493
I
L
T
Q
W
D
R
S
L
K
P
M
Q
T
R
Site 35
T499
R
S
L
K
P
M
Q
T
R
V
V
G
R
L
Q
Site 36
T532
I
A
V
F
L
V
L
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation