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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OTX1
Full Name:
Homeobox protein OTX1
Alias:
Orthodenticle homolog 1
Type:
Mass (Da):
37327
Number AA:
354
UniProt ID:
P32242
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
S
Y
L
K
Q
P
P
Y
G
M
N
G
L
G
L
Site 2
T34
P
S
V
G
Y
P
A
T
P
R
K
Q
R
R
E
Site 3
T43
R
K
Q
R
R
E
R
T
T
F
T
R
S
Q
L
Site 4
T44
K
Q
R
R
E
R
T
T
F
T
R
S
Q
L
D
Site 5
S48
E
R
T
T
F
T
R
S
Q
L
D
V
L
E
A
Site 6
Y62
A
L
F
A
K
T
R
Y
P
D
I
F
M
R
E
Site 7
S80
L
K
I
N
L
P
E
S
R
V
Q
V
W
F
K
Site 8
S99
K
C
R
Q
Q
Q
Q
S
G
S
G
T
K
S
R
Site 9
S101
R
Q
Q
Q
Q
S
G
S
G
T
K
S
R
P
A
Site 10
T103
Q
Q
Q
S
G
S
G
T
K
S
R
P
A
K
K
Site 11
S105
Q
S
G
S
G
T
K
S
R
P
A
K
K
K
S
Site 12
S112
S
R
P
A
K
K
K
S
S
P
V
R
E
S
S
Site 13
S113
R
P
A
K
K
K
S
S
P
V
R
E
S
S
G
Site 14
S118
K
S
S
P
V
R
E
S
S
G
S
E
S
S
G
Site 15
S119
S
S
P
V
R
E
S
S
G
S
E
S
S
G
Q
Site 16
S121
P
V
R
E
S
S
G
S
E
S
S
G
Q
F
T
Site 17
S123
R
E
S
S
G
S
E
S
S
G
Q
F
T
P
P
Site 18
S124
E
S
S
G
S
E
S
S
G
Q
F
T
P
P
A
Site 19
T128
S
E
S
S
G
Q
F
T
P
P
A
V
S
S
S
Site 20
S133
Q
F
T
P
P
A
V
S
S
S
A
S
S
S
S
Site 21
S134
F
T
P
P
A
V
S
S
S
A
S
S
S
S
S
Site 22
S135
T
P
P
A
V
S
S
S
A
S
S
S
S
S
A
Site 23
S137
P
A
V
S
S
S
A
S
S
S
S
S
A
S
S
Site 24
S138
A
V
S
S
S
A
S
S
S
S
S
A
S
S
S
Site 25
S139
V
S
S
S
A
S
S
S
S
S
A
S
S
S
S
Site 26
S140
S
S
S
A
S
S
S
S
S
A
S
S
S
S
A
Site 27
S141
S
S
A
S
S
S
S
S
A
S
S
S
S
A
N
Site 28
S143
A
S
S
S
S
S
A
S
S
S
S
A
N
P
A
Site 29
S144
S
S
S
S
S
A
S
S
S
S
A
N
P
A
A
Site 30
S145
S
S
S
S
A
S
S
S
S
A
N
P
A
A
A
Site 31
S146
S
S
S
A
S
S
S
S
A
N
P
A
A
A
A
Site 32
S174
S
L
S
T
P
A
A
S
S
I
W
S
P
A
S
Site 33
S178
P
A
A
S
S
I
W
S
P
A
S
I
S
P
G
Site 34
S181
S
S
I
W
S
P
A
S
I
S
P
G
S
A
P
Site 35
S183
I
W
S
P
A
S
I
S
P
G
S
A
P
A
S
Site 36
S190
S
P
G
S
A
P
A
S
V
S
V
P
E
P
L
Site 37
S201
P
E
P
L
A
A
P
S
N
T
S
C
M
Q
R
Site 38
S209
N
T
S
C
M
Q
R
S
V
A
A
G
A
A
T
Site 39
S220
G
A
A
T
A
A
A
S
Y
P
M
S
Y
G
Q
Site 40
Y221
A
A
T
A
A
A
S
Y
P
M
S
Y
G
Q
G
Site 41
S224
A
A
A
S
Y
P
M
S
Y
G
Q
G
G
S
Y
Site 42
Y225
A
A
S
Y
P
M
S
Y
G
Q
G
G
S
Y
G
Site 43
Y231
S
Y
G
Q
G
G
S
Y
G
Q
G
Y
P
T
P
Site 44
Y235
G
G
S
Y
G
Q
G
Y
P
T
P
S
S
S
Y
Site 45
T237
S
Y
G
Q
G
Y
P
T
P
S
S
S
Y
F
G
Site 46
S239
G
Q
G
Y
P
T
P
S
S
S
Y
F
G
G
V
Site 47
S240
Q
G
Y
P
T
P
S
S
S
Y
F
G
G
V
D
Site 48
S241
G
Y
P
T
P
S
S
S
Y
F
G
G
V
D
C
Site 49
Y251
G
G
V
D
C
S
S
Y
L
A
P
M
H
S
H
Site 50
S265
H
H
H
P
H
Q
L
S
P
M
A
P
S
S
M
Site 51
S271
L
S
P
M
A
P
S
S
M
A
G
H
H
H
H
Site 52
S287
P
H
A
H
H
P
L
S
Q
S
S
G
H
H
H
Site 53
Y304
H
H
H
H
H
Q
G
Y
G
G
S
G
L
A
F
Site 54
Y319
N
S
A
D
C
L
D
Y
K
E
P
G
A
A
A
Site 55
Y343
N
S
P
D
C
L
D
Y
K
D
Q
A
S
W
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation