KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
nAChRA3
Full Name:
Neuronal acetylcholine receptor subunit alpha-3
Alias:
Type:
Channel protein, chloride and cation
Mass (Da):
57310
Number AA:
503
UniProt ID:
P32297
International Prot ID:
IPI00743792
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0043025
GO:0030425
Uniprot
OncoNet
Molecular Function:
GO:0015464
GO:0004889
PhosphoSite+
KinaseNET
Biological Process:
GO:0007171
GO:0035095
GO:0006811
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y221
G
Y
K
H
D
I
K
Y
N
C
C
E
E
I
Y
Site 2
Y228
Y
N
C
C
E
E
I
Y
P
D
I
T
Y
S
L
Site 3
Y233
E
I
Y
P
D
I
T
Y
S
L
Y
I
R
R
L
Site 4
Y330
V
F
V
L
N
V
H
Y
R
T
P
T
T
H
T
Site 5
T332
V
L
N
V
H
Y
R
T
P
T
T
H
T
M
P
Site 6
T334
N
V
H
Y
R
T
P
T
T
H
T
M
P
S
W
Site 7
T357
L
P
R
V
M
F
M
T
R
P
T
S
N
E
G
Site 8
T360
V
M
F
M
T
R
P
T
S
N
E
G
N
A
Q
Site 9
S361
M
F
M
T
R
P
T
S
N
E
G
N
A
Q
K
Site 10
Y373
A
Q
K
P
R
P
L
Y
G
A
E
L
S
N
L
Site 11
S378
P
L
Y
G
A
E
L
S
N
L
N
C
F
S
R
Site 12
S384
L
S
N
L
N
C
F
S
R
A
E
S
K
G
C
Site 13
S388
N
C
F
S
R
A
E
S
K
G
C
K
E
G
Y
Site 14
Y395
S
K
G
C
K
E
G
Y
P
C
Q
D
G
M
C
Site 15
S413
H
H
R
R
I
K
I
S
N
F
S
A
N
L
T
Site 16
S416
R
I
K
I
S
N
F
S
A
N
L
T
R
S
S
Site 17
T420
S
N
F
S
A
N
L
T
R
S
S
S
S
E
S
Site 18
S422
F
S
A
N
L
T
R
S
S
S
S
E
S
V
D
Site 19
S423
S
A
N
L
T
R
S
S
S
S
E
S
V
D
A
Site 20
S424
A
N
L
T
R
S
S
S
S
E
S
V
D
A
V
Site 21
S427
T
R
S
S
S
S
E
S
V
D
A
V
L
S
L
Site 22
S447
E
I
K
E
A
I
Q
S
V
K
Y
I
A
E
N
Site 23
Y470
E
I
Q
D
D
W
K
Y
V
A
M
V
I
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation