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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSG3
Full Name:
Desmoglein-3
Alias:
130 kDa pemphigus vulgaris antigen;Cadherin family member 6
Type:
Mass (Da):
107533
Number AA:
999
UniProt ID:
P32926
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
H
G
E
L
R
I
E
T
K
G
Q
Y
D
E
E
Site 2
Y33
R
I
E
T
K
G
Q
Y
D
E
E
E
M
T
M
Site 3
T39
Q
Y
D
E
E
E
M
T
M
Q
Q
A
K
R
R
Site 4
S387
G
I
A
F
R
P
A
S
K
T
F
T
V
Q
K
Site 5
T389
A
F
R
P
A
S
K
T
F
T
V
Q
K
G
I
Site 6
T391
R
P
A
S
K
T
F
T
V
Q
K
G
I
S
S
Site 7
T706
S
S
E
V
C
T
N
T
Y
A
R
G
T
A
V
Site 8
Y707
S
E
V
C
T
N
T
Y
A
R
G
T
A
V
E
Site 9
T711
T
N
T
Y
A
R
G
T
A
V
E
G
T
S
G
Site 10
T723
T
S
G
M
E
M
T
T
K
L
G
A
A
T
E
Site 11
S760
T
G
V
G
I
C
S
S
G
Q
S
G
T
M
R
Site 12
S763
G
I
C
S
S
G
Q
S
G
T
M
R
T
R
H
Site 13
T768
G
Q
S
G
T
M
R
T
R
H
S
T
G
G
T
Site 14
S771
G
T
M
R
T
R
H
S
T
G
G
T
N
K
D
Site 15
T772
T
M
R
T
R
H
S
T
G
G
T
N
K
D
Y
Site 16
Y779
T
G
G
T
N
K
D
Y
A
D
G
A
I
S
M
Site 17
Y792
S
M
N
F
L
D
S
Y
F
S
Q
K
A
F
A
Site 18
Y816
A
N
D
C
L
L
I
Y
D
N
E
G
A
D
A
Site 19
T824
D
N
E
G
A
D
A
T
G
S
P
V
G
S
V
Site 20
S826
E
G
A
D
A
T
G
S
P
V
G
S
V
G
C
Site 21
S844
I
A
D
D
L
D
D
S
F
L
D
S
L
G
P
Site 22
S848
L
D
D
S
F
L
D
S
L
G
P
K
F
K
K
Site 23
S860
F
K
K
L
A
E
I
S
L
G
V
D
G
E
G
Site 24
S874
G
K
E
V
Q
P
P
S
K
D
S
G
Y
G
I
Site 25
S877
V
Q
P
P
S
K
D
S
G
Y
G
I
E
S
C
Site 26
Y879
P
P
S
K
D
S
G
Y
G
I
E
S
C
G
H
Site 27
T893
H
P
I
E
V
Q
Q
T
G
F
V
K
C
Q
T
Site 28
T900
T
G
F
V
K
C
Q
T
L
S
G
S
Q
G
A
Site 29
S902
F
V
K
C
Q
T
L
S
G
S
Q
G
A
S
A
Site 30
S904
K
C
Q
T
L
S
G
S
Q
G
A
S
A
L
S
Site 31
S908
L
S
G
S
Q
G
A
S
A
L
S
T
S
G
S
Site 32
S911
S
Q
G
A
S
A
L
S
T
S
G
S
V
Q
P
Site 33
T912
Q
G
A
S
A
L
S
T
S
G
S
V
Q
P
A
Site 34
S921
G
S
V
Q
P
A
V
S
I
P
D
P
L
Q
H
Site 35
Y931
D
P
L
Q
H
G
N
Y
L
V
T
E
T
Y
S
Site 36
T934
Q
H
G
N
Y
L
V
T
E
T
Y
S
A
S
G
Site 37
T936
G
N
Y
L
V
T
E
T
Y
S
A
S
G
S
L
Site 38
S942
E
T
Y
S
A
S
G
S
L
V
Q
P
S
T
A
Site 39
S947
S
G
S
L
V
Q
P
S
T
A
G
F
D
P
L
Site 40
T980
P
G
N
L
A
G
P
T
Q
L
R
G
S
H
T
Site 41
S985
G
P
T
Q
L
R
G
S
H
T
M
L
C
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation