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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CSF2RB
Full Name:
Cytokine receptor common subunit beta
Alias:
AIC2B; CD131; CDw131; Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); CSF2RB1; CYRB; Cytokine receptor common beta chain precursor; IL3RB; IL3RB1; IL5RB; IL-5R-B
Type:
Receptor, cytokine
Mass (Da):
97336
Number AA:
897
UniProt ID:
P32927
International Prot ID:
IPI00465234
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030526
Uniprot
OncoNet
Molecular Function:
GO:0004896
PhosphoSite+
KinaseNET
Biological Process:
GO:0019221
GO:0007585
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y466
A
L
R
F
C
G
I
Y
G
Y
R
L
R
R
K
Site 2
Y468
R
F
C
G
I
Y
G
Y
R
L
R
R
K
W
E
Site 3
S484
K
I
P
N
P
S
K
S
H
L
F
Q
N
G
S
Site 4
S491
S
H
L
F
Q
N
G
S
A
E
L
W
P
P
G
Site 5
S499
A
E
L
W
P
P
G
S
M
S
A
F
T
S
G
Site 6
S501
L
W
P
P
G
S
M
S
A
F
T
S
G
S
P
Site 7
T504
P
G
S
M
S
A
F
T
S
G
S
P
P
H
Q
Site 8
S505
G
S
M
S
A
F
T
S
G
S
P
P
H
Q
G
Site 9
S507
M
S
A
F
T
S
G
S
P
P
H
Q
G
P
W
Site 10
S516
P
H
Q
G
P
W
G
S
R
F
P
E
L
E
G
Site 11
S535
G
F
G
D
S
E
V
S
P
L
T
I
E
D
P
Site 12
T538
D
S
E
V
S
P
L
T
I
E
D
P
K
H
V
Site 13
S550
K
H
V
C
D
P
P
S
G
P
D
T
T
P
A
Site 14
T554
D
P
P
S
G
P
D
T
T
P
A
A
S
D
L
Site 15
T555
P
P
S
G
P
D
T
T
P
A
A
S
D
L
P
Site 16
S559
P
D
T
T
P
A
A
S
D
L
P
T
E
Q
P
Site 17
T563
P
A
A
S
D
L
P
T
E
Q
P
P
S
P
Q
Site 18
S568
L
P
T
E
Q
P
P
S
P
Q
P
G
P
P
A
Site 19
S577
Q
P
G
P
P
A
A
S
H
T
P
E
K
Q
A
Site 20
T579
G
P
P
A
A
S
H
T
P
E
K
Q
A
S
S
Site 21
S585
H
T
P
E
K
Q
A
S
S
F
D
F
N
G
P
Site 22
S586
T
P
E
K
Q
A
S
S
F
D
F
N
G
P
Y
Site 23
Y593
S
F
D
F
N
G
P
Y
L
G
P
P
H
S
R
Site 24
S599
P
Y
L
G
P
P
H
S
R
S
L
P
D
I
L
Site 25
S601
L
G
P
P
H
S
R
S
L
P
D
I
L
G
Q
Site 26
S617
E
P
P
Q
E
G
G
S
Q
K
S
P
P
P
G
Site 27
S620
Q
E
G
G
S
Q
K
S
P
P
P
G
S
L
E
Site 28
S625
Q
K
S
P
P
P
G
S
L
E
Y
L
C
L
P
Site 29
Y628
P
P
P
G
S
L
E
Y
L
C
L
P
A
G
G
Site 30
S659
V
E
V
E
R
R
P
S
Q
G
A
A
G
S
P
Site 31
S665
P
S
Q
G
A
A
G
S
P
S
L
E
S
G
G
Site 32
S667
Q
G
A
A
G
S
P
S
L
E
S
G
G
G
P
Site 33
S691
G
G
Q
D
Q
K
D
S
P
V
A
I
P
M
S
Site 34
S698
S
P
V
A
I
P
M
S
S
G
D
T
E
D
P
Site 35
T702
I
P
M
S
S
G
D
T
E
D
P
G
V
A
S
Site 36
S709
T
E
D
P
G
V
A
S
G
Y
V
S
S
A
D
Site 37
Y711
D
P
G
V
A
S
G
Y
V
S
S
A
D
L
V
Site 38
T720
S
S
A
D
L
V
F
T
P
N
S
G
A
S
S
Site 39
S738
V
P
S
L
G
L
P
S
D
Q
T
P
S
L
C
Site 40
S743
L
P
S
D
Q
T
P
S
L
C
P
G
L
A
S
Site 41
S761
G
A
P
G
P
V
K
S
G
F
E
G
Y
V
E
Site 42
Y766
V
K
S
G
F
E
G
Y
V
E
L
P
P
I
E
Site 43
S776
L
P
P
I
E
G
R
S
P
R
S
P
R
N
N
Site 44
S779
I
E
G
R
S
P
R
S
P
R
N
N
P
V
P
Site 45
S791
P
V
P
P
E
A
K
S
P
V
L
N
P
G
E
Site 46
S804
G
E
R
P
A
D
V
S
P
T
S
P
Q
P
E
Site 47
S807
P
A
D
V
S
P
T
S
P
Q
P
E
G
L
L
Site 48
Y822
V
L
Q
Q
V
G
D
Y
C
F
L
P
G
L
G
Site 49
S834
G
L
G
P
G
P
L
S
L
R
S
K
P
S
S
Site 50
S837
P
G
P
L
S
L
R
S
K
P
S
S
P
G
P
Site 51
S840
L
S
L
R
S
K
P
S
S
P
G
P
G
P
E
Site 52
S841
S
L
R
S
K
P
S
S
P
G
P
G
P
E
I
Site 53
Y882
K
A
L
K
Q
Q
D
Y
L
S
L
P
P
W
E
Site 54
S884
L
K
Q
Q
D
Y
L
S
L
P
P
W
E
V
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation