KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CSTF2
Full Name:
Cleavage stimulation factor subunit 2
Alias:
CF-1 64 kDa; Cleavage stimulation factor subunit 2; Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa; Cleavage stimulation factor, 64 kDa; Cleavage stimulation factor, 64kDa subunit; CSTF 64 kDa; CSTF 64 kDa subunit; CstF-64
Type:
RNA binding protein
Mass (Da):
60959
Number AA:
577
UniProt ID:
P33240
International Prot ID:
IPI00013256
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006379
GO:0006378
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
R
D
P
A
V
D
R
S
L
R
S
V
F
V
G
Site 2
Y25
V
F
V
G
N
I
P
Y
E
A
T
E
E
Q
L
Site 3
Y49
V
V
S
F
R
L
V
Y
D
R
E
T
G
K
P
Site 4
T53
R
L
V
Y
D
R
E
T
G
K
P
K
G
Y
G
Site 5
Y64
K
G
Y
G
F
C
E
Y
Q
D
Q
E
T
A
L
Site 6
S72
Q
D
Q
E
T
A
L
S
A
M
R
N
L
N
G
Site 7
S83
N
L
N
G
R
E
F
S
G
R
A
L
R
V
D
Site 8
S103
K
N
K
E
E
L
K
S
L
G
T
G
A
P
V
Site 9
S113
T
G
A
P
V
I
E
S
P
Y
G
E
T
I
S
Site 10
Y115
A
P
V
I
E
S
P
Y
G
E
T
I
S
P
E
Site 11
T118
I
E
S
P
Y
G
E
T
I
S
P
E
D
A
P
Site 12
S120
S
P
Y
G
E
T
I
S
P
E
D
A
P
E
S
Site 13
S127
S
P
E
D
A
P
E
S
I
S
K
A
V
A
S
Site 14
S154
M
K
L
C
V
Q
N
S
P
Q
E
A
R
N
M
Site 15
S215
V
H
G
A
G
P
G
S
G
S
N
V
S
M
N
Site 16
S217
G
A
G
P
G
S
G
S
N
V
S
M
N
Q
Q
Site 17
S220
P
G
S
G
S
N
V
S
M
N
Q
Q
N
P
Q
Site 18
S287
A
Q
V
G
M
P
G
S
G
P
V
S
M
E
R
Site 19
S291
M
P
G
S
G
P
V
S
M
E
R
G
Q
V
P
Site 20
S310
R
A
A
M
Q
R
G
S
L
P
A
N
V
P
T
Site 21
T317
S
L
P
A
N
V
P
T
P
R
G
L
L
G
D
Site 22
T333
P
N
D
P
R
G
G
T
L
L
S
V
T
G
E
Site 23
S336
P
R
G
G
T
L
L
S
V
T
G
E
V
E
P
Site 24
T338
G
G
T
L
L
S
V
T
G
E
V
E
P
R
G
Site 25
Y346
G
E
V
E
P
R
G
Y
L
G
P
P
H
Q
G
Site 26
S364
H
H
V
P
G
H
E
S
R
G
P
P
P
H
E
Site 27
T467
M
E
A
R
G
M
D
T
R
G
P
V
P
G
P
Site 28
S480
G
P
R
G
P
I
P
S
G
M
Q
G
P
S
P
Site 29
S486
P
S
G
M
Q
G
P
S
P
I
N
M
G
A
V
Site 30
S498
G
A
V
V
P
Q
G
S
R
Q
V
P
V
M
Q
Site 31
T507
Q
V
P
V
M
Q
G
T
G
M
Q
G
A
S
I
Site 32
S513
G
T
G
M
Q
G
A
S
I
Q
G
G
S
Q
P
Site 33
S518
G
A
S
I
Q
G
G
S
Q
P
G
G
F
S
P
Site 34
S524
G
S
Q
P
G
G
F
S
P
G
Q
N
Q
V
T
Site 35
T531
S
P
G
Q
N
Q
V
T
P
Q
D
H
E
K
A
Site 36
S562
L
P
P
E
Q
R
Q
S
I
L
I
L
K
E
Q
Site 37
S573
L
K
E
Q
I
Q
K
S
T
G
A
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation