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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LSP1
Full Name:
Lymphocyte-specific protein 1
Alias:
47 kDa actin binding protein; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; Protein pp52; WP34
Type:
Actin binding protein
Mass (Da):
37192
Number AA:
339
UniProt ID:
P33241
International Prot ID:
IPI00013260
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0006968
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
E
A
S
S
D
P
G
A
E
E
R
Site 2
S24
L
G
P
T
A
Q
W
S
V
E
D
E
E
E
A
Site 3
S66
P
K
Q
E
M
L
L
S
L
K
P
S
E
A
P
Site 4
S70
M
L
L
S
L
K
P
S
E
A
P
E
L
D
E
Site 5
S85
D
E
G
F
G
D
W
S
Q
R
P
E
Q
R
Q
Site 6
S103
G
A
Q
G
A
L
D
S
G
E
P
P
Q
C
R
Site 7
S111
G
E
P
P
Q
C
R
S
P
E
G
E
Q
E
D
Site 8
Y125
D
R
P
G
L
H
A
Y
E
K
E
D
S
D
E
Site 9
S130
H
A
Y
E
K
E
D
S
D
E
V
H
L
E
E
Site 10
S139
E
V
H
L
E
E
L
S
L
S
K
E
G
P
G
Site 11
S141
H
L
E
E
L
S
L
S
K
E
G
P
G
P
E
Site 12
T150
E
G
P
G
P
E
D
T
V
Q
D
N
L
G
A
Site 13
T175
Q
K
C
Q
Q
P
R
T
P
S
P
L
V
L
E
Site 14
S177
C
Q
Q
P
R
T
P
S
P
L
V
L
E
G
T
Site 15
T184
S
P
L
V
L
E
G
T
I
E
Q
S
S
P
P
Site 16
S188
L
E
G
T
I
E
Q
S
S
P
P
L
S
P
T
Site 17
S189
E
G
T
I
E
Q
S
S
P
P
L
S
P
T
T
Site 18
S193
E
Q
S
S
P
P
L
S
P
T
T
K
L
I
D
Site 19
T195
S
S
P
P
L
S
P
T
T
K
L
I
D
R
T
Site 20
T196
S
P
P
L
S
P
T
T
K
L
I
D
R
T
E
Site 21
T202
T
T
K
L
I
D
R
T
E
S
L
N
R
S
I
Site 22
S204
K
L
I
D
R
T
E
S
L
N
R
S
I
E
K
Site 23
S208
R
T
E
S
L
N
R
S
I
E
K
S
N
S
V
Site 24
S212
L
N
R
S
I
E
K
S
N
S
V
K
K
S
Q
Site 25
S214
R
S
I
E
K
S
N
S
V
K
K
S
Q
P
D
Site 26
S218
K
S
N
S
V
K
K
S
Q
P
D
L
P
I
S
Site 27
S225
S
Q
P
D
L
P
I
S
K
I
D
Q
W
L
E
Site 28
Y234
I
D
Q
W
L
E
Q
Y
T
Q
A
I
E
T
A
Site 29
T235
D
Q
W
L
E
Q
Y
T
Q
A
I
E
T
A
G
Site 30
T244
A
I
E
T
A
G
R
T
P
K
L
A
R
Q
A
Site 31
S252
P
K
L
A
R
Q
A
S
I
E
L
P
S
M
A
Site 32
S257
Q
A
S
I
E
L
P
S
M
A
V
A
S
T
K
Site 33
S265
M
A
V
A
S
T
K
S
R
W
E
T
G
E
V
Site 34
T269
S
T
K
S
R
W
E
T
G
E
V
Q
A
Q
S
Site 35
S276
T
G
E
V
Q
A
Q
S
A
A
K
T
P
S
C
Site 36
T280
Q
A
Q
S
A
A
K
T
P
S
C
K
D
I
V
Site 37
S282
Q
S
A
A
K
T
P
S
C
K
D
I
V
A
G
Site 38
S295
A
G
D
M
S
K
K
S
L
W
E
Q
K
G
G
Site 39
S303
L
W
E
Q
K
G
G
S
K
T
S
S
T
I
K
Site 40
T305
E
Q
K
G
G
S
K
T
S
S
T
I
K
S
T
Site 41
S307
K
G
G
S
K
T
S
S
T
I
K
S
T
P
S
Site 42
T308
G
G
S
K
T
S
S
T
I
K
S
T
P
S
G
Site 43
S311
K
T
S
S
T
I
K
S
T
P
S
G
K
R
Y
Site 44
T312
T
S
S
T
I
K
S
T
P
S
G
K
R
Y
K
Site 45
S314
S
T
I
K
S
T
P
S
G
K
R
Y
K
F
V
Site 46
Y318
S
T
P
S
G
K
R
Y
K
F
V
A
T
G
H
Site 47
T323
K
R
Y
K
F
V
A
T
G
H
G
K
Y
E
K
Site 48
Y328
V
A
T
G
H
G
K
Y
E
K
V
L
V
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation