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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCD1
Full Name:
ATP-binding cassette sub-family D member 1
Alias:
ABC42; Adrenoleukodystrophy protein; ALD; ALDP; AMN; ATP-binding cassette, sub-family D (ALD), 1
Type:
Transporter protein; Membrane, peroxisomal membrane, integral plasma membrane, peroxisome protein
Mass (Da):
82937
Number AA:
745
UniProt ID:
P33897
International Prot ID:
IPI00291373
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005779
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042626
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0033540
GO:0015919
GO:0007031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
P
R
P
W
R
G
N
T
L
K
R
T
A
V
L
Site 2
Y110
S
R
T
F
L
S
V
Y
V
A
R
L
D
G
R
Site 3
Y171
S
R
L
V
A
H
A
Y
R
L
Y
F
S
Q
Q
Site 4
Y174
V
A
H
A
Y
R
L
Y
F
S
Q
Q
T
Y
Y
Site 5
Y180
L
Y
F
S
Q
Q
T
Y
Y
R
V
S
N
M
D
Site 6
S184
Q
Q
T
Y
Y
R
V
S
N
M
D
G
R
L
R
Site 7
S196
R
L
R
N
P
D
Q
S
L
T
E
D
V
V
A
Site 8
T198
R
N
P
D
Q
S
L
T
E
D
V
V
A
F
A
Site 9
T240
A
R
S
R
G
A
G
T
A
W
P
S
A
I
A
Site 10
Y281
R
R
K
G
E
L
R
Y
M
H
S
R
V
V
A
Site 11
S290
H
S
R
V
V
A
N
S
E
E
I
A
F
Y
G
Site 12
Y296
N
S
E
E
I
A
F
Y
G
G
H
E
V
E
L
Site 13
S309
E
L
A
L
L
Q
R
S
Y
Q
D
L
A
S
Q
Site 14
Y310
L
A
L
L
Q
R
S
Y
Q
D
L
A
S
Q
I
Site 15
Y357
P
I
I
T
A
T
G
Y
S
E
S
D
A
E
A
Site 16
S358
I
I
T
A
T
G
Y
S
E
S
D
A
E
A
V
Site 17
S360
T
A
T
G
Y
S
E
S
D
A
E
A
V
K
K
Site 18
S379
K
K
E
E
E
L
V
S
E
R
T
E
A
F
T
Site 19
T386
S
E
R
T
E
A
F
T
I
A
R
N
L
L
T
Site 20
S404
D
A
I
E
R
I
M
S
S
Y
K
E
V
T
E
Site 21
S405
A
I
E
R
I
M
S
S
Y
K
E
V
T
E
L
Site 22
Y406
I
E
R
I
M
S
S
Y
K
E
V
T
E
L
A
Site 23
T410
M
S
S
Y
K
E
V
T
E
L
A
G
Y
T
A
Site 24
Y415
E
V
T
E
L
A
G
Y
T
A
R
V
H
E
M
Site 25
T416
V
T
E
L
A
G
Y
T
A
R
V
H
E
M
F
Site 26
T449
D
A
Q
A
G
S
G
T
I
G
R
S
G
V
R
Site 27
S453
G
S
G
T
I
G
R
S
G
V
R
V
E
G
P
Site 28
T506
E
G
M
H
L
L
I
T
G
P
N
G
C
G
K
Site 29
S514
G
P
N
G
C
G
K
S
S
L
F
R
I
L
G
Site 30
S515
P
N
G
C
G
K
S
S
L
F
R
I
L
G
G
Site 31
Y532
P
T
Y
G
G
V
L
Y
K
P
P
P
Q
R
M
Site 32
Y541
P
P
P
Q
R
M
F
Y
I
P
Q
R
P
Y
M
Site 33
Y547
F
Y
I
P
Q
R
P
Y
M
S
V
G
S
L
R
Site 34
S549
I
P
Q
R
P
Y
M
S
V
G
S
L
R
D
Q
Site 35
S552
R
P
Y
M
S
V
G
S
L
R
D
Q
V
I
Y
Site 36
Y559
S
L
R
D
Q
V
I
Y
P
D
S
V
E
D
M
Site 37
S562
D
Q
V
I
Y
P
D
S
V
E
D
M
Q
R
K
Site 38
Y571
E
D
M
Q
R
K
G
Y
S
E
Q
D
L
E
A
Site 39
Y620
I
G
M
A
R
M
F
Y
H
R
P
K
Y
A
L
Site 40
Y625
M
F
Y
H
R
P
K
Y
A
L
L
D
E
C
T
Site 41
Y666
H
R
P
S
L
W
K
Y
H
T
H
L
L
Q
F
Site 42
S686
W
K
F
E
K
L
D
S
A
A
R
L
S
L
T
Site 43
S691
L
D
S
A
A
R
L
S
L
T
E
E
K
Q
R
Site 44
T693
S
A
A
R
L
S
L
T
E
E
K
Q
R
L
E
Site 45
S733
P
A
H
V
P
A
P
S
P
Q
G
P
G
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation