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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAN1A1
Full Name:
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
Alias:
Man(9)-alpha-mannosidase;Mannosidase alpha class 1A member 1;Processing alpha-1,2-mannosidase IA
Type:
Mass (Da):
72969
Number AA:
653
UniProt ID:
P33908
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
L
L
P
L
F
S
S
P
A
G
G
V
L
G
Site 2
S31
G
G
G
G
R
K
G
S
G
P
A
A
L
R
L
Site 3
S70
P
D
S
S
K
L
L
S
G
V
L
F
H
S
S
Site 4
T138
A
L
R
E
A
K
E
T
L
Q
K
L
P
E
E
Site 5
S224
L
N
E
L
K
P
I
S
K
G
G
H
S
S
S
Site 6
S229
P
I
S
K
G
G
H
S
S
S
L
F
G
N
I
Site 7
S230
I
S
K
G
G
H
S
S
S
L
F
G
N
I
K
Site 8
S231
S
K
G
G
H
S
S
S
L
F
G
N
I
K
G
Site 9
S262
H
E
F
E
E
A
K
S
W
V
E
E
N
L
D
Site 10
S320
L
P
A
F
H
T
P
S
G
I
P
W
A
L
L
Site 11
S341
G
R
N
W
P
W
A
S
G
G
S
S
I
L
A
Site 12
S361
H
L
E
F
M
H
L
S
H
L
S
G
N
P
I
Site 13
Y390
L
E
K
P
Q
G
L
Y
P
N
Y
L
N
P
S
Site 14
Y393
P
Q
G
L
Y
P
N
Y
L
N
P
S
S
G
Q
Site 15
S407
Q
W
G
Q
H
H
V
S
V
G
G
L
G
D
S
Site 16
S414
S
V
G
G
L
G
D
S
F
Y
E
Y
L
L
K
Site 17
Y416
G
G
L
G
D
S
F
Y
E
Y
L
L
K
A
W
Site 18
S426
L
L
K
A
W
L
M
S
D
K
T
D
L
E
A
Site 19
T429
A
W
L
M
S
D
K
T
D
L
E
A
K
K
M
Site 20
Y437
D
L
E
A
K
K
M
Y
F
D
A
V
Q
A
I
Site 21
S452
E
T
H
L
I
R
K
S
S
S
G
L
T
Y
I
Site 22
S453
T
H
L
I
R
K
S
S
S
G
L
T
Y
I
A
Site 23
T457
R
K
S
S
S
G
L
T
Y
I
A
E
W
K
G
Site 24
Y458
K
S
S
S
G
L
T
Y
I
A
E
W
K
G
G
Site 25
Y497
P
E
G
M
A
Q
H
Y
L
E
L
G
A
E
I
Site 26
T507
L
G
A
E
I
A
R
T
C
H
E
S
Y
N
R
Site 27
Y512
A
R
T
C
H
E
S
Y
N
R
T
F
M
K
L
Site 28
T515
C
H
E
S
Y
N
R
T
F
M
K
L
G
P
E
Site 29
T535
G
G
V
E
A
I
A
T
R
Q
N
E
K
Y
Y
Site 30
Y541
A
T
R
Q
N
E
K
Y
Y
I
L
R
P
E
V
Site 31
Y552
R
P
E
V
M
E
T
Y
M
Y
M
W
R
L
T
Site 32
Y564
R
L
T
H
D
P
K
Y
R
K
W
A
W
E
A
Site 33
Y585
H
C
R
V
N
G
G
Y
S
G
L
R
D
V
Y
Site 34
Y592
Y
S
G
L
R
D
V
Y
L
L
H
E
S
Y
D
Site 35
S597
D
V
Y
L
L
H
E
S
Y
D
D
V
Q
Q
S
Site 36
Y598
V
Y
L
L
H
E
S
Y
D
D
V
Q
Q
S
F
Site 37
S604
S
Y
D
D
V
Q
Q
S
F
F
L
A
E
T
L
Site 38
Y615
A
E
T
L
K
Y
L
Y
L
I
F
S
D
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation