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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPA1L
Full Name:
Heat shock 70 kDa protein 1-like
Alias:
Heat shock 70 kDa protein 1-like; HS71L; HSP70-HOM; Hum70t
Type:
Uncharacterized protein
Mass (Da):
70375
Number AA:
641
UniProt ID:
P34931
International Prot ID:
IPI00304925
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006401
GO:0006402
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
G
I
D
L
G
T
T
Y
S
C
V
G
V
F
Q
Site 2
T40
N
D
Q
G
N
R
T
T
P
S
Y
V
A
F
T
Site 3
S42
Q
G
N
R
T
T
P
S
Y
V
A
F
T
D
T
Site 4
Y43
G
N
R
T
T
P
S
Y
V
A
F
T
D
T
E
Site 5
T49
S
Y
V
A
F
T
D
T
E
R
L
I
G
D
A
Site 6
T68
V
A
M
N
P
Q
N
T
V
F
D
A
K
R
L
Site 7
S108
G
K
P
K
V
L
V
S
Y
K
G
E
N
K
A
Site 8
Y109
K
P
K
V
L
V
S
Y
K
G
E
N
K
A
F
Site 9
Y117
K
G
E
N
K
A
F
Y
P
E
E
I
S
S
M
Site 10
S122
A
F
Y
P
E
E
I
S
S
M
V
L
T
K
L
Site 11
S123
F
Y
P
E
E
I
S
S
M
V
L
T
K
L
K
Site 12
T127
E
I
S
S
M
V
L
T
K
L
K
E
T
A
E
Site 13
T132
V
L
T
K
L
K
E
T
A
E
A
F
L
G
H
Site 14
Y151
A
V
I
T
V
P
A
Y
F
N
D
S
Q
R
Q
Site 15
S155
V
P
A
Y
F
N
D
S
Q
R
Q
A
T
K
D
Site 16
T160
N
D
S
Q
R
Q
A
T
K
D
A
G
V
I
A
Site 17
T179
L
R
I
I
N
E
P
T
A
A
A
I
A
Y
G
Site 18
T224
G
I
F
E
V
K
A
T
A
G
D
T
H
L
G
Site 19
T228
V
K
A
T
A
G
D
T
H
L
G
G
E
D
F
Site 20
S241
D
F
D
N
R
L
V
S
H
F
V
E
E
F
K
Site 21
S256
R
K
H
K
K
D
I
S
Q
N
K
R
A
V
R
Site 22
T267
R
A
V
R
R
L
R
T
A
C
E
R
A
K
R
Site 23
T275
A
C
E
R
A
K
R
T
L
S
S
S
T
Q
A
Site 24
S277
E
R
A
K
R
T
L
S
S
S
T
Q
A
N
L
Site 25
S279
A
K
R
T
L
S
S
S
T
Q
A
N
L
E
I
Site 26
S288
Q
A
N
L
E
I
D
S
L
Y
E
G
I
D
F
Site 27
Y290
N
L
E
I
D
S
L
Y
E
G
I
D
F
Y
T
Site 28
Y296
L
Y
E
G
I
D
F
Y
T
S
I
T
R
A
R
Site 29
S298
E
G
I
D
F
Y
T
S
I
T
R
A
R
F
E
Site 30
T300
I
D
F
Y
T
S
I
T
R
A
R
F
E
E
L
Site 31
T315
C
A
D
L
F
R
G
T
L
E
P
V
E
K
A
Site 32
Y355
V
Q
R
L
L
Q
D
Y
F
N
G
R
D
L
N
Site 33
S364
N
G
R
D
L
N
K
S
I
N
P
D
E
A
V
Site 34
Y373
N
P
D
E
A
V
A
Y
G
A
A
V
Q
A
A
Site 35
S387
A
I
L
M
G
D
K
S
E
K
V
Q
D
L
L
Site 36
S420
T
A
L
I
K
R
N
S
T
I
P
T
K
Q
T
Site 37
T421
A
L
I
K
R
N
S
T
I
P
T
K
Q
T
Q
Site 38
Y433
Q
T
Q
I
F
T
T
Y
S
D
N
Q
P
G
V
Site 39
T452
Y
E
G
E
R
A
M
T
K
D
N
N
L
L
G
Site 40
T464
L
L
G
R
F
D
L
T
G
I
P
P
A
P
R
Site 41
S496
N
V
T
A
T
D
K
S
T
G
K
V
N
K
I
Site 42
T504
T
G
K
V
N
K
I
T
I
T
N
D
K
G
R
Site 43
T506
K
V
N
K
I
T
I
T
N
D
K
G
R
L
S
Site 44
S513
T
N
D
K
G
R
L
S
K
E
E
I
E
R
M
Site 45
Y527
M
V
L
D
A
E
K
Y
K
A
E
D
E
V
Q
Site 46
Y547
A
K
N
A
L
E
S
Y
A
F
N
M
K
S
V
Site 47
S553
S
Y
A
F
N
M
K
S
V
V
S
D
E
G
L
Site 48
S565
E
G
L
K
G
K
I
S
E
S
D
K
N
K
I
Site 49
S567
L
K
G
K
I
S
E
S
D
K
N
K
I
L
D
Site 50
Y613
N
P
I
I
T
K
L
Y
Q
G
G
C
T
G
P
Site 51
Y626
G
P
A
C
G
T
G
Y
V
P
G
R
P
A
T
Site 52
T633
Y
V
P
G
R
P
A
T
G
P
T
I
E
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation