PhosphoNET

           
Protein Info 
   
Short Name:  Cx37
Full Name:  Gap junction alpha-4 protein
Alias:  connexin 37; CX37; gap junction protein, alpha 4, 37kDa
Type:  Membrane protein, integral; Adhesion
Mass (Da):  37410
Number AA: 
UniProt ID:  P35212
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005922  GO:0005887   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0007043     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y98VYLGHVIYLSRREER
Site 2S100LGHVIYLSRREERLR
Site 3Y177LYGQWRLYGWTMEPV
Site 4S237HLLCRCLSRGMRARQ
Site 5T251QGQDAPPTQGTSSDP
Site 6S256PPTQGTSSDPYTDQV
Site 7Y259QGTSSDPYTDQVFFY
Site 8T260GTSSDPYTDQVFFYL
Site 9Y266YTDQVFFYLPVGQGP
Site 10S274LPVGQGPSSPPCPTY
Site 11S275PVGQGPSSPPCPTYN
Site 12T280PSSPPCPTYNGLSSS
Site 13Y281SSPPCPTYNGLSSSE
Site 14S287TYNGLSSSEQNWANL
Site 15S302TTEERLASSRPPLFL
Site 16S321QNGQKPPSRPSSSAS
Site 17S324QKPPSRPSSSASKKQ
Site 18S325KPPSRPSSSASKKQY
Site 19S326PPSRPSSSASKKQYV
Site 20S328SRPSSSASKKQYV__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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