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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTNNA1
Full Name:
Catenin alpha-1
Alias:
102 kDa cadherin-associated protein; Alpha E-catenin; Cadherin-associated protein; Catenin, alpha-1; CATNA1; CTN1; CTNA1
Type:
Cytoskeletal protein; Plasma membrane, cytoplasm, cell junction and actin associated
Mass (Da):
100071
Number AA:
906
UniProt ID:
P35221
International Prot ID:
IPI00215948
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005912
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0045296
GO:0005198
GO:0017166
PhosphoSite+
KinaseNET
Biological Process:
GO:0043297
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
N
F
K
W
D
P
K
S
L
E
I
R
T
L
A
Site 2
T38
P
L
V
T
Q
V
T
T
L
V
N
T
N
S
K
Site 3
T42
Q
V
T
T
L
V
N
T
N
S
K
G
P
S
N
Site 4
S44
T
T
L
V
N
T
N
S
K
G
P
S
N
K
K
Site 5
S48
N
T
N
S
K
G
P
S
N
K
K
R
G
R
S
Site 6
S55
S
N
K
K
R
G
R
S
K
K
A
H
V
L
A
Site 7
S83
G
D
K
I
A
K
E
S
Q
F
L
K
E
E
L
Site 8
S117
E
F
A
D
D
P
C
S
S
V
K
R
G
N
M
Site 9
S118
F
A
D
D
P
C
S
S
V
K
R
G
N
M
V
Site 10
Y148
L
A
D
M
A
D
V
Y
K
L
L
V
Q
L
K
Site 11
Y177
E
Q
D
L
G
I
Q
Y
K
A
L
K
P
E
V
Site 12
Y222
Q
K
N
V
P
I
L
Y
T
A
S
Q
A
C
L
Site 13
T223
K
N
V
P
I
L
Y
T
A
S
Q
A
C
L
Q
Site 14
Y237
Q
H
P
D
V
A
A
Y
K
A
N
R
D
L
I
Site 15
Y245
K
A
N
R
D
L
I
Y
K
Q
L
Q
Q
A
V
Site 16
S264
N
A
A
Q
A
T
A
S
D
D
A
S
Q
H
Q
Site 17
S268
A
T
A
S
D
D
A
S
Q
H
Q
G
G
G
G
Site 18
Y280
G
G
G
G
E
L
A
Y
A
L
N
N
F
D
K
Site 19
S295
Q
I
I
V
D
P
L
S
F
S
E
E
R
F
R
Site 20
S297
I
V
D
P
L
S
F
S
E
E
R
F
R
P
S
Site 21
S304
S
E
E
R
F
R
P
S
L
E
E
R
L
E
S
Site 22
S323
A
A
L
M
A
D
S
S
C
T
R
D
D
R
R
Site 23
S349
Q
A
L
Q
D
L
L
S
E
Y
M
G
N
A
G
Site 24
Y351
L
Q
D
L
L
S
E
Y
M
G
N
A
G
R
K
Site 25
S361
N
A
G
R
K
E
R
S
D
A
L
N
S
A
I
Site 26
T372
N
S
A
I
D
K
M
T
K
K
T
R
D
L
R
Site 27
S391
K
A
V
M
D
H
V
S
D
S
F
L
E
T
N
Site 28
S393
V
M
D
H
V
S
D
S
F
L
E
T
N
V
P
Site 29
Y419
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Site 30
S441
A
N
L
A
C
S
I
S
N
N
E
E
G
V
K
Site 31
S455
K
L
V
R
M
S
A
S
Q
L
E
A
L
C
P
Site 32
T499
E
K
Q
V
R
V
L
T
D
A
V
D
D
I
T
Site 33
S515
I
D
D
F
L
A
V
S
E
N
H
I
L
E
D
Site 34
T541
D
V
D
G
L
D
R
T
A
G
A
I
R
G
R
Site 35
Y563
V
T
S
E
M
D
N
Y
E
P
G
V
Y
T
E
Site 36
Y568
D
N
Y
E
P
G
V
Y
T
E
K
V
L
E
A
Site 37
T582
A
T
K
L
L
S
N
T
V
M
P
R
F
T
E
Site 38
T588
N
T
V
M
P
R
F
T
E
Q
V
E
A
A
V
Site 39
S600
A
A
V
E
A
L
S
S
D
P
A
Q
P
M
D
Site 40
Y619
I
D
A
S
R
L
V
Y
D
G
I
R
D
I
R
Site 41
T634
K
A
V
L
M
I
R
T
P
E
E
L
D
D
S
Site 42
S641
T
P
E
E
L
D
D
S
D
F
E
T
E
D
F
Site 43
T645
L
D
D
S
D
F
E
T
E
D
F
D
V
R
S
Site 44
S652
T
E
D
F
D
V
R
S
R
T
S
V
Q
T
E
Site 45
T654
D
F
D
V
R
S
R
T
S
V
Q
T
E
D
D
Site 46
S655
F
D
V
R
S
R
T
S
V
Q
T
E
D
D
Q
Site 47
T658
R
S
R
T
S
V
Q
T
E
D
D
Q
L
I
A
Site 48
S668
D
Q
L
I
A
G
Q
S
A
R
A
I
M
A
Q
Site 49
S690
K
I
A
E
Q
V
A
S
F
Q
E
E
K
S
K
Site 50
S703
S
K
L
D
A
E
V
S
K
W
D
D
S
G
N
Site 51
S708
E
V
S
K
W
D
D
S
G
N
D
I
I
V
L
Site 52
T730
M
M
E
M
T
D
F
T
R
G
K
G
P
L
K
Site 53
S740
K
G
P
L
K
N
T
S
D
V
I
S
A
A
K
Site 54
S744
K
N
T
S
D
V
I
S
A
A
K
K
I
A
E
Site 55
S754
K
K
I
A
E
A
G
S
R
M
D
K
L
G
R
Site 56
Y779
C
K
Q
D
L
L
A
Y
L
Q
R
I
A
L
Y
Site 57
S817
S
G
V
D
S
A
M
S
L
I
Q
A
A
K
N
Site 58
Y837
V
Q
T
V
K
A
S
Y
V
A
S
T
K
Y
Q
Site 59
S840
V
K
A
S
Y
V
A
S
T
K
Y
Q
K
S
Q
Site 60
Y843
S
Y
V
A
S
T
K
Y
Q
K
S
Q
G
M
A
Site 61
S846
A
S
T
K
Y
Q
K
S
Q
G
M
A
S
L
N
Site 62
S851
Q
K
S
Q
G
M
A
S
L
N
L
P
A
V
S
Site 63
T878
K
R
E
K
Q
D
E
T
Q
T
K
I
K
R
A
Site 64
S886
Q
T
K
I
K
R
A
S
Q
K
K
H
V
N
P
Site 65
S898
V
N
P
V
Q
A
L
S
E
F
K
A
M
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation