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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB6
Full Name:
Serpin B6
Alias:
CAP; Cytoplasmic antiproteinase; MSTP057; PI6; PI-6; Placental thrombin inhibitor; Proteinase inhibitor 6; PTI; Serpin peptidase inhibitor, clade B (ovalbumin), member 6; SPB6; SPI3
Type:
Protease inhibitor
Mass (Da):
42622
Number AA:
376
UniProt ID:
P35237
International Prot ID:
IPI00413451
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
F
A
L
N
L
L
K
T
L
G
K
D
N
S
K
Site 2
S24
K
T
L
G
K
D
N
S
K
N
V
F
F
S
P
Site 3
S30
N
S
K
N
V
F
F
S
P
M
S
M
S
C
A
Site 4
Y42
S
C
A
L
A
M
V
Y
M
G
A
K
G
N
T
Site 5
S58
A
Q
M
A
Q
I
L
S
F
N
K
S
G
G
G
Site 6
S62
Q
I
L
S
F
N
K
S
G
G
G
G
D
I
H
Site 7
S74
D
I
H
Q
G
F
Q
S
L
L
T
E
V
N
K
Site 8
T77
Q
G
F
Q
S
L
L
T
E
V
N
K
T
G
T
Site 9
T82
L
L
T
E
V
N
K
T
G
T
Q
Y
L
L
R
Site 10
Y86
V
N
K
T
G
T
Q
Y
L
L
R
M
A
N
R
Site 11
S99
N
R
L
F
G
E
K
S
C
D
F
L
S
S
F
Site 12
S104
E
K
S
C
D
F
L
S
S
F
R
D
S
C
Q
Site 13
S105
K
S
C
D
F
L
S
S
F
R
D
S
C
Q
K
Site 14
S109
F
L
S
S
F
R
D
S
C
Q
K
F
Y
Q
A
Site 15
S125
M
E
E
L
D
F
I
S
A
V
E
K
S
R
K
Site 16
T136
K
S
R
K
H
I
N
T
W
V
A
E
K
T
E
Site 17
S151
G
K
I
A
E
L
L
S
P
G
S
V
D
P
L
Site 18
Y168
L
V
L
V
N
A
V
Y
F
R
G
N
W
D
E
Site 19
S190
E
E
R
L
F
K
V
S
K
N
E
E
K
P
V
Site 20
T205
Q
M
M
F
K
Q
S
T
F
K
K
T
Y
I
G
Site 21
T239
I
M
L
P
D
E
T
T
D
L
R
T
V
E
K
Site 22
T243
D
E
T
T
D
L
R
T
V
E
K
E
L
T
Y
Site 23
T249
R
T
V
E
K
E
L
T
Y
E
K
F
V
E
W
Site 24
Y250
T
V
E
K
E
L
T
Y
E
K
F
V
E
W
T
Site 25
S270
D
E
E
E
V
E
V
S
L
P
R
F
K
L
E
Site 26
S279
P
R
F
K
L
E
E
S
Y
D
M
E
S
V
L
Site 27
Y280
R
F
K
L
E
E
S
Y
D
M
E
S
V
L
R
Site 28
S284
E
E
S
Y
D
M
E
S
V
L
R
N
L
G
M
Site 29
S306
K
A
D
F
S
G
M
S
Q
T
D
L
S
L
S
Site 30
S311
G
M
S
Q
T
D
L
S
L
S
K
V
V
H
K
Site 31
S313
S
Q
T
D
L
S
L
S
K
V
V
H
K
S
F
Site 32
S319
L
S
K
V
V
H
K
S
F
V
E
V
N
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation