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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RFC4
Full Name:
Replication factor C subunit 4
Alias:
A1 37 kDa; Activator 1 37 kDa; Replication factor C 37 kDa; Replication factor C 37 kDa subunit; RF-C 37 kDa; RFC37
Type:
DNA replication protein
Mass (Da):
39682
Number AA:
363
UniProt ID:
P35249
International Prot ID:
IPI00017381
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005654
GO:0005663
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
Q
A
F
L
K
G
T
S
I
S
T
K
P
P
L
Site 2
S11
F
L
K
G
T
S
I
S
T
K
P
P
L
T
K
Site 3
T12
L
K
G
T
S
I
S
T
K
P
P
L
T
K
D
Site 4
T17
I
S
T
K
P
P
L
T
K
D
R
G
V
A
A
Site 5
S25
K
D
R
G
V
A
A
S
A
G
S
S
G
E
N
Site 6
S28
G
V
A
A
S
A
G
S
S
G
E
N
K
K
A
Site 7
S29
V
A
A
S
A
G
S
S
G
E
N
K
K
A
K
Site 8
Y77
D
L
P
N
L
L
F
Y
G
P
P
G
T
G
K
Site 9
S111
R
V
L
E
L
N
A
S
D
E
R
G
I
Q
V
Site 10
T130
V
K
N
F
A
Q
L
T
V
S
G
S
R
S
D
Site 11
S132
N
F
A
Q
L
T
V
S
G
S
R
S
D
G
K
Site 12
S134
A
Q
L
T
V
S
G
S
R
S
D
G
K
P
C
Site 13
S136
L
T
V
S
G
S
R
S
D
G
K
P
C
P
P
Site 14
S157
D
E
A
D
S
M
T
S
A
A
Q
A
A
L
R
Site 15
T166
A
Q
A
A
L
R
R
T
M
E
K
E
S
K
T
Site 16
T173
T
M
E
K
E
S
K
T
T
R
F
C
L
I
C
Site 17
Y182
R
F
C
L
I
C
N
Y
V
S
R
I
I
E
P
Site 18
T191
S
R
I
I
E
P
L
T
S
R
C
S
K
F
R
Site 19
S192
R
I
I
E
P
L
T
S
R
C
S
K
F
R
F
Site 20
S195
E
P
L
T
S
R
C
S
K
F
R
F
K
P
L
Site 21
S203
K
F
R
F
K
P
L
S
D
K
I
Q
Q
Q
R
Site 22
S223
K
K
E
N
V
K
I
S
D
E
G
I
A
Y
L
Site 23
T243
G
D
L
R
K
A
I
T
F
L
Q
S
A
T
R
Site 24
T252
L
Q
S
A
T
R
L
T
G
G
K
E
I
T
E
Site 25
S320
V
V
V
E
N
N
L
S
D
K
Q
K
S
I
I
Site 26
S325
N
L
S
D
K
Q
K
S
I
I
T
E
K
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation