PhosphoNET

           
Protein Info 
   
Short Name:  PTGER4
Full Name:  Prostaglandin E2 receptor EP4 subtype
Alias:  Prostanoid EP4 receptor
Type:  G protein-coupled 7TM receptor
Mass (Da):  53119
Number AA:  488
UniProt ID:  P35408
International Prot ID:  IPI00018648
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005886   Uniprot OncoNet
Molecular Function:  GO:0004957     PhosphoSite+ KinaseNET
Biological Process:  GO:0007188  GO:0006955   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MSTPGVNSSASLSPD
Site 2S9STPGVNSSASLSPDR
Site 3S11PGVNSSASLSPDRLN
Site 4S13VNSSASLSPDRLNSP
Site 5S45AIVVLCKSRKEQKET
Site 6T52SRKEQKETTFYTLVC
Site 7T53RKEQKETTFYTLVCG
Site 8Y80SPVTIATYMKGQWPG
Site 9Y125YLAINHAYFYSHYVD
Site 10Y130HAYFYSHYVDKRLAG
Site 11S160LPNMGLGSSRLQYPD
Site 12S161PNMGLGSSRLQYPDT
Site 13Y165LGSSRLQYPDTWCFI
Site 14Y186TAHAAYSYMYAGFSS
Site 15T221HRQFMRRTSLGTEQH
Site 16S222RQFMRRTSLGTEQHH
Site 17S235HHAAAAASVASRGHP
Site 18S245SRGHPAASPALPRLS
Site 19S252SPALPRLSDFRRRRS
Site 20S259SDFRRRRSFRRIAGA
Site 21Y298RVFVNQLYQPSLERE
Site 22S301VNQLYQPSLEREVSK
Site 23S307PSLEREVSKNPDLQA
Site 24S338LLRKTVLSKAIEKIK
Site 25S354LFCRIGGSRRERSGQ
Site 26S359GGSRRERSGQHCSDS
Site 27S364ERSGQHCSDSQRTSS
Site 28S366SGQHCSDSQRTSSAM
Site 29S370CSDSQRTSSAMSGHS
Site 30S371SDSQRTSSAMSGHSR
Site 31S374QRTSSAMSGHSRSFI
Site 32S377SSAMSGHSRSFISRE
Site 33S379AMSGHSRSFISRELK
Site 34S382GHSRSFISRELKEIS
Site 35S389SRELKEISSTSQTLL
Site 36S390RELKEISSTSQTLLP
Site 37T391ELKEISSTSQTLLPD
Site 38S392LKEISSTSQTLLPDL
Site 39T394EISSTSQTLLPDLSL
Site 40S400QTLLPDLSLPDLSEN
Site 41S405DLSLPDLSENGLGGR
Site 42T428MGLAQEDTTSLRTLR
Site 43S430LAQEDTTSLRTLRIS
Site 44T433EDTTSLRTLRISETS
Site 45S437SLRTLRISETSDSSQ
Site 46T439RTLRISETSDSSQGQ
Site 47S440TLRISETSDSSQGQD
Site 48S442RISETSDSSQGQDSE
Site 49S443ISETSDSSQGQDSES
Site 50S448DSSQGQDSESVLLVD
Site 51S450SQGQDSESVLLVDEA
Site 52S460LVDEAGGSGRAGPAP
Site 53T475KGSSLQVTFPSETLN
Site 54T480QVTFPSETLNLSEKC
Site 55S484PSETLNLSEKCI___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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