KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HOXD13
Full Name:
Homeobox protein Hox-D13
Alias:
Homeobox protein Hox-4I
Type:
Mass (Da):
36101
Number AA:
343
UniProt ID:
P35453
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
G
A
G
G
A
P
A
S
S
S
S
S
S
V
A
Site 2
Y76
A
A
A
S
G
F
A
Y
P
G
T
S
E
R
T
Site 3
T79
S
G
F
A
Y
P
G
T
S
E
R
T
G
S
S
Site 4
S80
G
F
A
Y
P
G
T
S
E
R
T
G
S
S
S
Site 5
T83
Y
P
G
T
S
E
R
T
G
S
S
S
S
S
S
Site 6
S85
G
T
S
E
R
T
G
S
S
S
S
S
S
S
S
Site 7
S86
T
S
E
R
T
G
S
S
S
S
S
S
S
S
A
Site 8
S87
S
E
R
T
G
S
S
S
S
S
S
S
S
A
V
Site 9
S88
E
R
T
G
S
S
S
S
S
S
S
S
A
V
V
Site 10
S89
R
T
G
S
S
S
S
S
S
S
S
A
V
V
A
Site 11
S90
T
G
S
S
S
S
S
S
S
S
A
V
V
A
A
Site 12
S91
G
S
S
S
S
S
S
S
S
A
V
V
A
A
R
Site 13
S92
S
S
S
S
S
S
S
S
A
V
V
A
A
R
P
Site 14
Y127
P
S
A
P
A
L
G
Y
G
Y
H
F
G
N
G
Site 15
Y129
A
P
A
L
G
Y
G
Y
H
F
G
N
G
Y
Y
Site 16
Y136
Y
H
F
G
N
G
Y
Y
S
C
R
M
S
H
G
Site 17
S153
L
Q
Q
N
A
L
K
S
S
P
H
A
S
L
G
Site 18
S154
Q
Q
N
A
L
K
S
S
P
H
A
S
L
G
G
Site 19
S158
L
K
S
S
P
H
A
S
L
G
G
F
P
V
E
Site 20
S175
M
D
V
S
G
L
A
S
S
S
V
P
A
N
E
Site 21
S191
P
A
R
A
K
E
V
S
F
Y
Q
G
Y
T
S
Site 22
Y193
R
A
K
E
V
S
F
Y
Q
G
Y
T
S
P
Y
Site 23
Y196
E
V
S
F
Y
Q
G
Y
T
S
P
Y
Q
H
V
Site 24
S198
S
F
Y
Q
G
Y
T
S
P
Y
Q
H
V
P
G
Site 25
Y200
Y
Q
G
Y
T
S
P
Y
Q
H
V
P
G
Y
I
Site 26
Y206
P
Y
Q
H
V
P
G
Y
I
D
M
V
S
T
F
Site 27
S211
P
G
Y
I
D
M
V
S
T
F
G
S
G
E
P
Site 28
T212
G
Y
I
D
M
V
S
T
F
G
S
G
E
P
R
Site 29
S215
D
M
V
S
T
F
G
S
G
E
P
R
H
E
A
Site 30
Y223
G
E
P
R
H
E
A
Y
I
S
M
E
G
Y
Q
Site 31
Y229
A
Y
I
S
M
E
G
Y
Q
S
W
T
L
A
N
Site 32
Y243
N
G
W
N
S
Q
V
Y
C
T
K
D
Q
P
Q
Site 33
S252
T
K
D
Q
P
Q
G
S
H
F
W
K
S
S
F
Site 34
S257
Q
G
S
H
F
W
K
S
S
F
P
G
D
V
A
Site 35
S258
G
S
H
F
W
K
S
S
F
P
G
D
V
A
L
Site 36
Y273
N
Q
P
D
M
C
V
Y
R
R
G
R
K
K
R
Site 37
Y283
G
R
K
K
R
V
P
Y
T
K
L
Q
L
K
E
Site 38
S310
K
D
K
R
R
R
I
S
A
A
T
N
L
S
E
Site 39
T313
R
R
R
I
S
A
A
T
N
L
S
E
R
Q
V
Site 40
S316
I
S
A
A
T
N
L
S
E
R
Q
V
T
I
W
Site 41
T321
N
L
S
E
R
Q
V
T
I
W
F
Q
N
R
R
Site 42
S336
V
K
D
K
K
I
V
S
K
L
K
D
T
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation